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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Intra Oral Kinetics of Fluoride Containing Dentifrices

Not Applicable
Completed
Conditions
Tooth Erosion
Interventions
Other: Comparator Dentifrice
Other: Test Dentifrice
Other: Reference Dentifrice
Other: Orange Juice
Other: De-ionised water
First Posted Date
2015-09-14
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
29
Registration Number
NCT02548156
Locations
🇬🇧

GSK Investigational Site, Ellesmere Port, Cheshire, United Kingdom

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the Investigational GSK Biologicals' GSK3277511A Vaccine in Adults.

Phase 1
Completed
Conditions
Respiratory Disorders
Interventions
Drug: Placebo
First Posted Date
2015-09-14
Last Posted Date
2018-08-31
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
120
Registration Number
NCT02547974
Locations
🇧🇪

GSK Investigational Site, Wilrijk, Belgium

A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.

Phase 3
Completed
Conditions
Virus Diseases
Rabies
Interventions
Biological: Rabipur
Procedure: Blood sampling
Biological: Purified Chick-Embryo Cell Rabies Vaccine
First Posted Date
2015-09-10
Last Posted Date
2024-07-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
459
Registration Number
NCT02545517
Locations
🇨🇭

GSK Investigational Site, Zuerich, Switzerland

Safety, Tolerability and Pharmacokinetics (PK) Study of Oxytocin (GR121619) Administered Via an Inhaled Route in Healthy Female Volunteers

Phase 1
Completed
Conditions
Postpartum Hemorrhage
Interventions
Drug: IM oxytocin 10 IU
Drug: IH oxytocin 50 mcg
Drug: IH oxytocin 200 mcg
Drug: IH oxytocin 400 mcg
Drug: IH oxytocin 600 mcg
Drug: Placebo
First Posted Date
2015-09-07
Last Posted Date
2017-10-19
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
16
Registration Number
NCT02542813
Locations
🇬🇧

GSK Investigational Site, Cambridge, United Kingdom

A Study to Investigate the Impact of Fortified Malt Based on Immunity Outcomes in School Children

Not Applicable
Completed
Conditions
Growth and Development
Interventions
Dietary Supplement: Fortified malt based food
First Posted Date
2015-09-07
Last Posted Date
2019-12-05
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
924
Registration Number
NCT02542865
Locations
🇮🇳

GSK Investigational Site, Pune, India

Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

Not Applicable
Completed
Conditions
Dentin Sensitivity
Interventions
Device: Experimental Oral Rinse 1
Device: Experimental Oral Rinse 2
Other: Placebo Oral Rinse
Drug: Standard fluoride toothpaste
First Posted Date
2015-09-07
Last Posted Date
2017-03-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
240
Registration Number
NCT02542943
Locations
🇺🇸

GSK Investigational Site, Las Vegas, Nevada, United States

In Vivo Investigation of Initial Stages of Enamel Erosion

Not Applicable
Completed
Conditions
Tooth Erosion
Interventions
Other: Sodium fluoride + potassium nitrate
Other: Potassium nitrate
First Posted Date
2015-08-26
Last Posted Date
2017-08-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
30
Registration Number
NCT02533466
Locations
🇬🇧

GSK Investigational Site, Bristol, United Kingdom

Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis

Phase 3
Terminated
Conditions
Giant Cell Arteritis
Interventions
Drug: Placebo to match sirukumab
Drug: Placebo to match prednisone
First Posted Date
2015-08-24
Last Posted Date
2019-07-31
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
161
Registration Number
NCT02531633
Locations
🇬🇧

GSK Investigational Site, Reading, United Kingdom

GSK3174998 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors (ENGAGE-1)

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2015-08-19
Last Posted Date
2021-05-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
141
Registration Number
NCT02528357
Locations
🇳🇱

GSK Investigational Site, Amsterdam, Netherlands

A Study to Evaluate the Safety, Efficacy and Changes in Induced Sputum and Blood Biomarkers Following Daily Repeat Doses of Inhaled GSK2269557 in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Acute Exacerbation

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Placebo
Device: ELLIPTA
Device: DISKUS
First Posted Date
2015-08-13
Last Posted Date
2021-09-05
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
44
Registration Number
NCT02522299
Locations
🇩🇰

GSK Investigational Site, Odense, Denmark

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