GlaxoSmithKline

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Public

Established: 1929-01-01

Employees: 70.2K

Market Cap: $90B

Website: http://www.gsk.com

Introduction: GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients

Phase 1

Completed

Conditions: Hypertension, Pulmonary

Interventions: Drug: [11C]-GSK2256098 500 MBq

First Posted Date: 2015-09-16

Last Posted Date: 2018-11-14

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 10

Registration Number: NCT02551653

Locations: 🇬🇧
GSK Investigational Site, London, United Kingdom

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the Investigational GSK Biologicals' GSK3277511A Vaccine in Adults.

Phase 1

Completed

Conditions: Respiratory Disorders

Interventions: Drug: Placebo

First Posted Date: 2015-09-14

Last Posted Date: 2018-08-31

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 120

Registration Number: NCT02547974

Locations: 🇧🇪
GSK Investigational Site, Wilrijk, Belgium

A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children

Phase 2

Completed

Conditions: Virus Diseases

Interventions: Biological: GlaxoSmithKline (GSK) Biologicals' investigational recombinant chimpanzee adenovirus Type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) (GSK3390107A)
Biological: Nimenrix powder and solvent for solution for injection in pre-filled syringe; Meningococcal group A, C, W-135 and Y conjugate vaccine

First Posted Date: 2015-09-14

Last Posted Date: 2018-05-03

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 600

Registration Number: NCT02548078

Locations: 🇸🇳
GSK Investigational Site, Dakar, Senegal

Intra Oral Kinetics of Fluoride Containing Dentifrices

Not Applicable

Completed

Conditions: Tooth Erosion

Interventions: Other: Comparator Dentifrice
Other: Test Dentifrice
Other: Reference Dentifrice
Other: Orange Juice
Other: De-ionised water

First Posted Date: 2015-09-14

Last Posted Date: 2017-01-18

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 29

Registration Number: NCT02548156

Locations: 🇬🇧
GSK Investigational Site, Ellesmere Port, Cheshire, United Kingdom

Study of Safety and Efficacy of Topical GSK2981278 Ointment in Plaque Psoriasis

Phase 1

Completed

Conditions: Psoriasis

Interventions: Drug: GSK2981278 0.03%
Drug: GSK2981278 0.1%
Drug: GSK2981278 0.8%
Drug: GSK2981278 4%
Drug: Vehicle
Drug: Betamethasone valerate 0.1%

First Posted Date: 2015-09-14

Last Posted Date: 2017-05-15

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 15

Registration Number: NCT02548052

Locations: 🇩🇪
GSK Investigational Site, Hamburg, Germany

A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.

Phase 3

Completed

Conditions: Virus Diseases
Rabies

Interventions: Biological: Rabipur
Procedure: Blood sampling
Biological: Purified Chick-Embryo Cell Rabies Vaccine

First Posted Date: 2015-09-10

Last Posted Date: 2024-07-18

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 459

Registration Number: NCT02545517

Locations: 🇨🇭
GSK Investigational Site, Zuerich, Switzerland

Safety, Tolerability and Pharmacokinetics (PK) Study of Oxytocin (GR121619) Administered Via an Inhaled Route in Healthy Female Volunteers

Phase 1

Completed

Conditions: Postpartum Hemorrhage

Interventions: Drug: IM oxytocin 10 IU
Drug: IH oxytocin 50 mcg
Drug: IH oxytocin 200 mcg
Drug: IH oxytocin 400 mcg
Drug: IH oxytocin 600 mcg
Drug: Placebo