MedPath

Ohsu Knight Cancer Institute

🇺🇸United States
Ownership
Subsidiary
Employees
-
Market Cap
-
Website
http://www.ohsu.edu/knight-cancer-institute

Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome

Phase 2
Not yet recruiting
Conditions
Hematopoietic and Lymphatic System Neoplasm
Interventions
Procedure: Biospecimen Collection
Procedure: Lumbar Puncture
First Posted Date
2025-03-26
Last Posted Date
2025-03-26
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
22
Registration Number
NCT06895473
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Vaccine Responses in Patient with Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

Recruiting
Conditions
Chronic Lymphocytic Leukemia
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Multiple Myeloma
Primary Mediastinal Large B-Cell Lymphoma
Small Lymphocytic Lymphoma
First Posted Date
2025-01-20
Last Posted Date
2025-03-20
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
45
Registration Number
NCT06784167
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

Not Applicable
Recruiting
Conditions
Clinical Stage IA Cutaneous Melanoma AJCC v8
Clinical Stage IB Cutaneous Melanoma AJCC v8
Clinical Stage IIA Cutaneous Melanoma AJCC v8
First Posted Date
2024-11-04
Last Posted Date
2024-12-18
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
1000
Registration Number
NCT06673095
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients with Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

Phase 2
Not yet recruiting
Conditions
Advanced Breast Carcinoma
Advanced Malignant Solid Neoplasm
Advanced Ovarian Carcinoma
Advanced Pancreatic Carcinoma
Advanced Prostate Carcinoma
Advanced Sarcoma
Anatomic Stage III Breast Cancer AJCC V8
Anatomic Stage IV Breast Cancer AJCC V8
Stage III Ovarian Cancer AJCC V8
Stage III Pancreatic Cancer AJCC V8
Interventions
First Posted Date
2024-10-08
Last Posted Date
2025-02-13
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
30
Registration Number
NCT06630325
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer

Recruiting
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
Other: Non-Interventional Study
First Posted Date
2024-08-20
Last Posted Date
2025-04-18
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
90
Registration Number
NCT06562777
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer

Phase 2
Recruiting
Conditions
High Risk Prostate Carcinoma
Stage I Prostate Cancer AJCC v8
Stage II Prostate Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Localized Prostate Adenocarcinoma
Interventions
Drug: Gonadotropin Releasing Hormone Agonists and Antagonists
Procedure: Biopsy
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Magnetic Resonance Imaging
Other: Questionnaire Administration
Radiation: Radiation Therapy
Procedure: Bone Scan
First Posted Date
2024-07-30
Last Posted Date
2025-05-21
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
32
Registration Number
NCT06528210
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Venetoclax in Combination with Cladribine and Cytarabine Alternating with Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia
Acute Monocytic Leukemia
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Aspiration
Procedure: Bone Marrow Biopsy
Procedure: Echocardiography
Procedure: Lumbar Puncture
Procedure: Multigated Acquisition Scan
Other: Questionnaire Administration
First Posted Date
2024-07-16
Last Posted Date
2025-03-10
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
40
Registration Number
NCT06504459
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Phase 2
Withdrawn
Conditions
Locally Advanced Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Unresectable Pancreatic Adenocarcinoma
Interventions
Procedure: Electrocardiography
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Procedure: Biospecimen Collection
Procedure: Computed Tomography
First Posted Date
2024-05-03
Last Posted Date
2024-07-19
Lead Sponsor
OHSU Knight Cancer Institute
Registration Number
NCT06398587
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

Phase 1
Recruiting
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndrome/Acute Myeloid Leukemia
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Biopsy
Procedure: Echocardiography
Procedure: Multigated Acquisition Scan
Other: Questionnaire Administration
First Posted Date
2024-04-10
Last Posted Date
2025-01-20
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
24
Registration Number
NCT06357182
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma

Phase 1
Not yet recruiting
Conditions
Mantle Cell Lymphoma
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Biopsy
Procedure: Computed Tomography
Procedure: Echocardiography
Procedure: FDG-Positron Emission Tomography
Procedure: Magnetic Resonance Imaging
First Posted Date
2024-04-10
Last Posted Date
2025-04-20
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
27
Registration Number
NCT06357676
Locations
🇺🇸

OHSU Knight Cancer Institute, Portland, Oregon, United States

© Copyright 2025. All Rights Reserved by MedPath