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Aravive

Aravive logo
🇺🇸United States
Ownership
Public
Established
2008-12-10
Employees
23
Market Cap
-
Website
http://www.aravive.com
Introduction

Aravive Inc is a clinical-stage biopharmaceutical company. It focuses on developing treatments designed to halt the progression of life-threatening diseases, including cancer and fibrosis. The company pipeline product Batiraxcept (formerly AVB-500) which is an ultra-high affinity decoy protein that binds to GAS6 and thereby prevents AXL signaling to inhibit metastasis and tumor growth and restore sensitivity to anti-cancer agents. Batiraxcept is currently being evaluated in multiple clinical trials.

Clinical Trials

12

Active:6
Completed:2

Trial Phases

3 Phases

Phase 1:10
Phase 2:1
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (12 trials with phase data)• Click on a phase to view related trials

Phase 1
10 (83.3%)
Phase 2
1 (8.3%)
Phase 3
1 (8.3%)

Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma

Phase 1
Terminated
Conditions
Pancreatic Adenocarcinoma
Interventions
First Posted Date
2021-07-30
Last Posted Date
2023-10-30
Lead Sponsor
Aravive, Inc.
Target Recruit Count
34
Registration Number
NCT04983407
Locations
🇺🇸

UCLA Health, Santa Monica, California, United States

🇺🇸

Boca Raton Regional Hospital / Lynn Cancer Institute, Boca Raton, Florida, United States

🇺🇸

Moffit Cancer Center, Tampa, Florida, United States

and more 14 locations

Batiraxcept (AVB-S6-500)/Placebo in Combination With Paclitaxel in Patients With Platinum-Resistant Recurrent Ovarian Cancer

Phase 3
Terminated
Conditions
Platinum-resistant Ovarian Cancer
Interventions
First Posted Date
2021-01-28
Last Posted Date
2023-10-30
Lead Sponsor
Aravive, Inc.
Target Recruit Count
366
Registration Number
NCT04729608
Locations
🇺🇸

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States

🇺🇸

Disney Family Cancer Center, Burbank, California, United States

🇺🇸

Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States

and more 146 locations

Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced or Metastatic Clear Cell Renal Cell Carcinoma

Phase 1
Terminated
Conditions
Clear Cell Renal Cell Carcinoma
Interventions
First Posted Date
2020-03-09
Last Posted Date
2023-10-30
Lead Sponsor
Aravive, Inc.
Target Recruit Count
72
Registration Number
NCT04300140
Locations
🇺🇸

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

and more 14 locations

Study of Safety and Efficacy of AVB-S6-500 in Patients With IgA Nephropathy

Phase 2
Terminated
Conditions
IgA Nephropathy
Interventions
First Posted Date
2019-08-02
Last Posted Date
2022-02-10
Lead Sponsor
Aravive, Inc.
Target Recruit Count
1
Registration Number
NCT04042623
Locations
🇺🇸

Moonshine Clinical Research, Doral, Florida, United States

🇺🇦

Institute of Nephrology National Academy of Medical Science Ukraine, Kyiv, Ukraine

Efficacy and Safety Study of AVB-S6-500 in Patients With Platinum-Resistant Recurrent Ovarian Cancer

Phase 1
Completed
Conditions
Ovarian Cancer
Interventions
First Posted Date
2018-08-21
Last Posted Date
2023-02-13
Lead Sponsor
Aravive, Inc.
Target Recruit Count
53
Registration Number
NCT03639246
Locations
🇺🇸

Arizona Oncology, Phoenix, Arizona, United States

🇺🇸

Arizona Oncology Associates, Tucson, Arizona, United States

🇺🇸

Kaiser Permanente Oakland, Oakland, California, United States

and more 13 locations
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