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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

Phase 3
Recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2023-11-20
Last Posted Date
2025-05-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
190
Registration Number
NCT06140836
Locations
🇺🇸

Local Institution - 0136, Augusta, Georgia, United States

🇺🇸

Local Institution - 0221, Des Moines, Iowa, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 141 locations

A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Multiple Sclerosis and Their Infants

Active, not recruiting
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2023-11-15
Last Posted Date
2023-11-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
2961
Registration Number
NCT06133049
Locations
🇺🇸

OptumInsight Life Sciences Inc, Eden Prairie, Minnesota, United States

A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Ulcerative Colitis and Their Infants

Active, not recruiting
Conditions
Ulcerative Colitis
Interventions
Drug: Conventional therapy
Drug: Advanced therapy
First Posted Date
2023-11-13
Last Posted Date
2024-10-01
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
2828
Registration Number
NCT06126835
Locations
🇺🇸

OptumInsight Life Sciences Inc, Eden Prairie, Minnesota, United States

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

Phase 2
Recruiting
Conditions
Heart Failure
Interventions
Other: Placebo
First Posted Date
2023-11-08
Last Posted Date
2025-05-28
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
198
Registration Number
NCT06122779
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Local Institution - 0096, Lakewood, Colorado, United States

🇺🇸

Local Institution - 0077, Jacksonville, Florida, United States

and more 112 locations

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Phase 4
Recruiting
Conditions
Cardiomyopathy, Hypertrophic
Interventions
First Posted Date
2023-11-01
Last Posted Date
2025-06-04
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
85
Registration Number
NCT06112743
Locations
🇮🇹

Local Institution - 0048, Firenze, Toscana, Italy

🇮🇹

Local Institution - 0062, Pisa, Toscana, Italy

🇮🇹

Local Institution - 0051, Arezzo, Italy

and more 86 locations

A Study to Evaluate Deucravacitinib in Participants With Moderate-to-Severe Plaque Psoriasis in Germany

Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2023-10-27
Last Posted Date
2025-06-04
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
550
Registration Number
NCT06104644
Locations
🇩🇪

Local Institution - 0001, Selters, Germany

🇩🇪

Dermatologische Spezial- und Schwerpunktpraxis Selters, Selters, Rhineland-Palatinate, Germany

A Study to Evaluate Whether Participants With Melanoma Prefer Subcutaneous vs Intravenous Administration of Nivolumab and Nivolumab + Relatlimab Fixed-dose Combinations

Phase 2
Active, not recruiting
Conditions
Melanoma
Interventions
Drug: relatlimab+nivolumab
Drug: nivolumab+rHuPH20
Drug: relatlimab+nivolumab+rHuPH20
First Posted Date
2023-10-26
Last Posted Date
2025-04-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
100
Registration Number
NCT06101134
Locations
🇺🇸

Local Institution - 0036, Issaquah, Washington, United States

🇺🇸

Local Institution - 0030, Seattle, Washington, United States

🇬🇷

Local Institution - 0019, Thessaloniki, B, Greece

and more 28 locations

A Study of BMS-986315 and Nivolumab in Combination With Chemotherapy in Participants With First-line Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)

First Posted Date
2023-10-23
Last Posted Date
2025-04-16
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
1
Registration Number
NCT06094296
Locations
🇺🇸

Local Institution - 0058, Boise, Idaho, United States

🇺🇸

Local Institution - 0044, Clermont, Florida, United States

🇺🇸

Local Institution - 0049, Houston, Texas, United States

and more 5 locations

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

Phase 1
Recruiting
Conditions
Relapsed/Refractory Non-Hodgkin Lymphoma
Interventions
First Posted Date
2023-10-19
Last Posted Date
2024-08-28
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
273
Registration Number
NCT06090539
Locations
🇩🇪

Universitätsklinikum Leipzig, Leipzig, Sachsen, Germany

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 19 locations

A Study to Evaluate the Drug Levels, Metabolism, and Removal of BMS-986322 in Healthy Adult Male Participants

Phase 1
Completed
Conditions
Healthy Male Participants
Interventions
First Posted Date
2023-10-18
Last Posted Date
2024-03-29
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
8
Registration Number
NCT06088264
Locations
🇺🇸

Fortrea Clinical Research Unit, Madison, Wisconsin, United States

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