Children's Oncology Group

🇺🇸United States
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Clinical Trials
Related News

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

First Posted Date
2024-10-18
Last Posted Date
2024-12-05
Lead Sponsor
Children's Oncology Group
Target Recruit Count
110
Registration Number
NCT06647953

A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home

First Posted Date
2024-10-15
Last Posted Date
2024-12-18
Lead Sponsor
Children's Oncology Group
Target Recruit Count
64
Registration Number
NCT06639958
Locations
🇺🇸

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida, United States

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

First Posted Date
2024-10-01
Last Posted Date
2024-10-07
Lead Sponsor
Children's Oncology Group
Target Recruit Count
81
Registration Number
NCT06620302

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

First Posted Date
2024-07-22
Last Posted Date
2024-09-30
Lead Sponsor
Children's Oncology Group
Target Recruit Count
60
Registration Number
NCT06513962

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

First Posted Date
2024-05-13
Last Posted Date
2024-12-04
Lead Sponsor
Children's Oncology Group
Target Recruit Count
190
Registration Number
NCT06410209
Locations
🇺🇸

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida, United States

🇺🇸

Yale University, New Haven, Connecticut, United States

🇺🇸

Riley Hospital for Children, Indianapolis, Indiana, United States

and more 31 locations

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

First Posted Date
2024-05-06
Last Posted Date
2024-12-20
Lead Sponsor
Children's Oncology Group
Target Recruit Count
1656
Registration Number
NCT06401330

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

First Posted Date
2024-04-16
Last Posted Date
2024-12-05
Lead Sponsor
Children's Oncology Group
Target Recruit Count
240
Registration Number
NCT06368817
Locations
🇺🇸

Loma Linda University Medical Center, Loma Linda, California, United States

🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Lucile Packard Children's Hospital Stanford University, Palo Alto, California, United States

and more 19 locations

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

First Posted Date
2024-02-08
Last Posted Date
2024-12-04
Lead Sponsor
Children's Oncology Group
Target Recruit Count
36
Registration Number
NCT06247787
Locations
🇺🇸

Children's Hospital Colorado, Aurora, Colorado, United States

🇺🇸

C S Mott Children's Hospital, Ann Arbor, Michigan, United States

🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

and more 10 locations

Somatic Mosaicism in Twins Discordant for Childhood Cancer

First Posted Date
2023-09-26
Last Posted Date
2024-06-21
Lead Sponsor
Children's Oncology Group
Target Recruit Count
50
Registration Number
NCT06054295
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Phase 2
Recruiting
Conditions
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Recurrent Mixed Phenotype Acute Leukemia
Recurrent Acute Leukemia of Ambiguous Lineage
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Recurrent Acute Lymphoblastic Leukemia
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Refractory Acute Leukemia of Ambiguous Lineage
Refractory Acute Lymphoblastic Leukemia
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Aspiration
Drug: Cytarabine
Drug: Calaspargase Pegol
Procedure: Echocardiography
Drug: Fludarabine Phosphate
Drug: Hydrocortisone Sodium Succinate
Procedure: Lumbar Puncture
Drug: Methotrexate
Procedure: Multigated Acquisition Scan
Drug: Prednisolone
Drug: Prednisone
Drug: Revumenib
Drug: Vincristine Sulfate
First Posted Date
2023-03-09
Last Posted Date
2024-12-04
Lead Sponsor
Children's Oncology Group
Target Recruit Count
78
Registration Number
NCT05761171
Locations
🇺🇸

Kaiser Permanente Downey Medical Center, Downey, California, United States

🇺🇸

Renown Regional Medical Center, Reno, Nevada, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 62 locations
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