DeepMed Research

Ottawa Hospital Research Institute

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 2001-01-01

Employees: 5K

Market Cap: -

Website: http://www.ohri.ca

Clinical Trials

Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer

Phase 4

Active, not recruiting

Conditions: Breast Cancer
Castration-resistant Prostate Cancer

Interventions: Drug: Bone modifying agent

First Posted Date: 2020-09-16

Last Posted Date: 2024-07-24

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 240

Registration Number: NCT04549207

Locations: 🇨🇦
The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada

One Versus Two Unit Transfusions in Oncology Patients - The OTTOP Trial: A Randomized Open-label Pragmatic Controlled Trial

Not Applicable

Not yet recruiting

Conditions: Anemia
Oncology

Interventions: Other: Units of transfusion

First Posted Date: 2020-09-10

Last Posted Date: 2020-09-10

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 450

Registration Number: NCT04544540

Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC

Phase 2

Recruiting

Conditions: Bladder Cancer

Interventions: Drug: Durvalumab
Radiation: Immune Modulating Radiation

First Posted Date: 2020-09-09

Last Posted Date: 2023-03-23

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 16

Registration Number: NCT04543110

Locations: 🇨🇦
Cross Cancer Institute, Edmonton, Alberta, Canada
🇨🇦
Juravinski Cancer Centre, Hamilton, Ontario, Canada
🇨🇦
London Health Sciences Centre, London, Ontario, Canada

and more 1 locations

Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients

Phase 4

Completed

Conditions: Fluid Therapy

Interventions: Drug: Ringer's lactate
Drug: 0.9% saline

First Posted Date: 2020-08-14

Last Posted Date: 2025-05-02

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 43626

Registration Number: NCT04512950

Locations: 🇨🇦
Queensway Carleton Hospital, Ottawa, Ontario, Canada
🇨🇦
Hamilton General Hospital, Hamilton, Ontario, Canada
🇨🇦
The Ottawa Hospital Civic Campus, Ottawa, Ontario, Canada

and more 4 locations

Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients

Phase 2

Conditions: Covid19

Interventions: Drug: Oxygen

First Posted Date: 2020-08-05

Last Posted Date: 2021-11-01

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 234

Registration Number: NCT04500626

Locations: 🇨🇦
The Ottawa Hospital, Ottawa, Ontario, Canada
🇨🇦
Rouge Valley Hyperbaric Medical Centre, Scarborough, Ontario, Canada

RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department

Phase 4

Completed

Conditions: Atrial Fibrillation

Interventions: Drug: Procainamide
Drug: Vernakalant

First Posted Date: 2020-07-24

Last Posted Date: 2025-04-10

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 350

Registration Number: NCT04485195

Locations: 🇨🇦
University of Alberta Hospital, Edmonton, Alberta, Canada
🇨🇦
Vancouver General Hospital, Vancouver, British Columbia, Canada
🇨🇦
Montreal Heart Institute, Montreal, Quebec, Canada

and more 11 locations

High-dose vs. Standard-dose Cephalexin for Cellulitis

Phase 4

Completed

Conditions: Cellulitis

Interventions: Drug: Cephalexin
Drug: Cephalexin + placebo

First Posted Date: 2020-07-15

Last Posted Date: 2025-01-17

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 69

Registration Number: NCT04471246

Locations: 🇨🇦
The Ottawa Hospital, Ottawa, Ontario, Canada

Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation

Phase 3

Completed

Conditions: COVID
Mechanical Ventilation
Sedation
Critical Illness

Interventions: Drug: Propranolol Hydrochloride

First Posted Date: 2020-07-10

Last Posted Date: 2022-12-05

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 72

Registration Number: NCT04467086

Locations: 🇨🇦
Hamilton Health Sciences Centre - Hamilton General Hospital, Hamilton, Ontario, Canada
🇨🇦
The Ottawa Hospital, Ottawa, Ontario, Canada

Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department

Not Applicable

Withdrawn

Conditions: Vomiting
Nausea

Interventions: Other: Isopropyl alcohol swab

First Posted Date: 2020-07-09

Last Posted Date: 2022-09-30

Lead Sponsor: Ottawa Hospital Research Institute

Registration Number: NCT04464915

Locations: 🇨🇦
The Ottawa Hospital, Ottawa, Ontario, Canada

Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial)

Phase 3

Recruiting

Conditions: Hematologic Neoplasms

Interventions: Drug: Tranexamic Acid

First Posted Date: 2020-06-25

Last Posted Date: 2023-09-21

Lead Sponsor: Ottawa Hospital Research Institute

Target Recruit Count: 662

Registration Number: NCT04448184

Locations: 🇨🇦
Dalhousie University, Halifax, Nova Scotia, Canada
🇨🇦
Memorial University, St. John's, Newfoundland and Labrador, Canada
🇨🇦
Eastern Regional Health Authority, Saint John's, Newfoundland and Labrador, Canada

and more 8 locations

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