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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
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🇺🇸
United States
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Clinical Trials
Related News
A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection
Phase 2
Completed
Conditions
Influenza A Virus
Interventions
Drug: Placebo
Drug: JNJ-63623872
Drug: Oseltamivir
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First Posted Date
2015-08-25
Last Posted Date
2020-03-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
102
Registration Number
NCT02532283
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A Study of Daratumumab With the Addition of Recombinant Human Hyaluronidase (rHuPH20) for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma
Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
Drug: Daratumumab Subcutaneous (SC) Administration
Drug: Recombinant Human Hyaluronidase [rHuPH20]) SC Administration
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First Posted Date
2015-08-11
Last Posted Date
2024-03-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
120
Registration Number
NCT02519452
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An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress
Phase 2
Completed
Conditions
Depressive Disorder
Anxiety
Interventions
Other: Placebo
Drug: JNJ-42165279
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First Posted Date
2015-07-15
Last Posted Date
2022-11-10
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
161
Registration Number
NCT02498392
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A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression
Phase 3
Completed
Conditions
Treatment-resistant Depression
Interventions
Drug: Esketamine (Intranasal Spray)
Drug: Duloxetine (Oral Antidepressant)
Drug: Escitalopram (Oral Antidepressant)
Drug: Sertraline (Oral Antidepressant)
Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant)
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First Posted Date
2015-07-14
Last Posted Date
2020-05-06
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
802
Registration Number
NCT02497287
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A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression
Phase 3
Completed
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
Drug: Placebo
Drug: Esketamine
Drug: Duloxetine (Oral Antidepressant)
Drug: Escitalopram (Oral antidepressant)
Drug: Sertraline (Oral Antidepressant)
Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant)
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First Posted Date
2015-07-10
Last Posted Date
2020-06-02
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
719
Registration Number
NCT02493868
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Study to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD)
Completed
Conditions
Depressive Disorder, Major
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First Posted Date
2015-07-03
Last Posted Date
2018-10-26
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
330
Registration Number
NCT02489305
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Early Access Treatment With Daratumumab for (Relapsed or Refractory) Multiple Myeloma
Conditions
Multiple Myeloma
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First Posted Date
2015-06-23
Last Posted Date
2019-01-15
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT02477891
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A Study to Investigate the Effect of Increased Gastric pH on the Oral Bioavailability of the Orexin-2 Receptor Antagonist JNJ-42847922 in Healthy Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42847922
Drug: Rabeprazole
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First Posted Date
2015-06-18
Last Posted Date
2016-01-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
16
Registration Number
NCT02475161
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An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder
Phase 2
Completed
Conditions
Depressive Disorder, Major
Interventions
Drug: Sirukumab 50 mg
Drug: Placebo
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First Posted Date
2015-06-16
Last Posted Date
2019-06-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
193
Registration Number
NCT02473289
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An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy
Phase 2
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
Drug: Decitabine 20 mg/m^2
Drug: Talacotuzumab 9 mg/kg
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First Posted Date
2015-06-15
Last Posted Date
2019-03-19
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
326
Registration Number
NCT02472145
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