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JANSSEN RESEARCH & DEVELOPMENT, LLC

🇺🇸United States
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A Study of a Self-Administered Memory Screening Test With Automated Reporting (SAMSTAR) in Participants With Mild Cognitive Impairment

Completed
Conditions
Mild Cognitive Impairment
Interventions
Other: SAMSTAR
Other: RAVLT
First Posted Date
2015-04-17
Last Posted Date
2016-07-01
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
153
Registration Number
NCT02419183

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Phase 3
Completed
Conditions
Treatment-resistant Depression
Interventions
Drug: Placebo
Drug: Esketamine
Drug: Duloxetine (Oral Antidepressant)
Drug: Escitalopram (Oral antidepressant)
Drug: Sertraline (Oral Antidepressant)
Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant)
First Posted Date
2015-04-16
Last Posted Date
2020-06-02
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
236
Registration Number
NCT02418585

An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma

Phase 2
Terminated
Conditions
Lymphoma, Mantle-Cell
Lymphoma, Large B-Cell, Diffuse
Lymphoma, Follicular
Interventions
First Posted Date
2015-04-10
Last Posted Date
2018-06-26
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
36
Registration Number
NCT02413489

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Phase 3
Completed
Conditions
Colitis, Ulcerative
Inflammatory Bowel Diseases
Interventions
Drug: Ustekinumab IV
Drug: Ustekinumab SC
Drug: Placebo IV
Drug: Placebo SC
First Posted Date
2015-04-02
Last Posted Date
2023-01-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
961
Registration Number
NCT02407236

An Efficacy and Safety Study of Ustekinumab in Participants With Active Nonradiographic Axial Spondyloarthritis

Phase 3
Terminated
Conditions
Nonradiographic Axial Spondylitis, Ankylosing
First Posted Date
2015-04-02
Last Posted Date
2019-03-13
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
356
Registration Number
NCT02407223

An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum

Phase 2
Terminated
Conditions
Alzheimer Disease
Interventions
Drug: JNJ-54861911, 10 mg
Drug: JNJ-54861911, 25 mg
Drug: Placebo
Drug: JNJ-54861911, 5 mg
First Posted Date
2015-04-01
Last Posted Date
2023-06-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
90
Registration Number
NCT02406027

Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy

Phase 1
Completed
Conditions
B-Cell Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2015-03-06
Last Posted Date
2017-06-26
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
26
Registration Number
NCT02381080
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