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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
Country
🇺🇸
United States
Ownership
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Clinical Trials
Related News
An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy
Phase 2
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
Drug: Decitabine 20 mg/m^2
Drug: Talacotuzumab 9 mg/kg
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First Posted Date
2015-06-15
Last Posted Date
2019-03-19
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
326
Registration Number
NCT02472145
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A Study in Participants With Psoriatic Arthritis Attending Dermatology Clinics
Completed
Conditions
Psoriatic Arthritis
Interventions
Other: No Intervention
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First Posted Date
2015-06-12
Last Posted Date
2016-09-02
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
250
Registration Number
NCT02470481
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A Study to Assess the Relative Bioavailability of JNJ-42756493 Tablets
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42756493 Current Clinical Formulation (G-018)
Drug: JNJ-42756493 Prototype Formulation I (G-025)
Drug: JNJ-42756493 Prototype Formulation II (G-025)
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First Posted Date
2015-06-09
Last Posted Date
2025-02-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
12
Registration Number
NCT02466815
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Study to Evaluate Efficacy, Safety and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder Without Psychiatric Comorbidity
Phase 2
Completed
Conditions
Insomnia
Interventions
Drug: JNJ-42847922
Drug: Placebo
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First Posted Date
2015-06-08
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
28
Registration Number
NCT02464046
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A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass Spectrometry
Phase 2
Terminated
Conditions
Schizophrenia
Schizoaffective Disorder
Interventions
Drug: Aripiprazole
Drug: Olanzapine
Drug: Paliperidone
Drug: Quetiapine
Drug: Risperidone
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First Posted Date
2015-06-04
Last Posted Date
2017-03-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
9
Registration Number
NCT02462473
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A Dose Escalation Study of Duvortuxizumab in Participants With Relapsed or Refractory B-cell Malignancies
Phase 1
Terminated
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, Mantle-Cell
Lymphoma, Large B-Cell, Diffuse
Lymphoma, Follicular
Precursor Cell Lymphoblastic Leukemia-Lymphoma
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First Posted Date
2015-05-27
Last Posted Date
2018-12-20
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
59
Registration Number
NCT02454270
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A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNF(Alpha) Refractory Participants With Active Radiographic Axial Spondyloarthritis
Phase 3
Terminated
Conditions
Axial Spondyloarthritis
Interventions
Drug: Ustekinumab 90 mg
Drug: Placebo
Drug: Ustekinumab 45 mg
Drug: Golimumab 50 mg
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First Posted Date
2015-05-08
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
315
Registration Number
NCT02438787
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A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants With Active Radiographic Axial Spondyloarthritis
Phase 3
Terminated
Conditions
Axial Spondyloarthritis
Interventions
Drug: Placebo
Drug: Ustekinumab 45 mg
Drug: Ustekinumab 90 mg
Drug: Golimumab 50 mg
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First Posted Date
2015-05-07
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
347
Registration Number
NCT02437162
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A Safety and Efficacy Study of JNJ-42165279 in Participants With Social Anxiety Disorder
Phase 2
Completed
Conditions
Phobic Disorders
Interventions
Drug: Placebo
Drug: JNJ-42165279
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First Posted Date
2015-05-04
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
150
Registration Number
NCT02432703
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A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression
Phase 3
Completed
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
Drug: Placebo
Drug: Esketamine
Drug: Duloxetine (Oral Antidepressant)
Drug: Escitalopram (Oral Antidepressant)
Drug: Sertraline (Oral Antidepressant)
Drug: Venlafaxine Extended Release (XR) (New Antidepressant)
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First Posted Date
2015-04-21
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
139
Registration Number
NCT02422186
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