Cyclacel Pharmaceuticals

Cyclacel Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1996-01-01
Employees
12
Market Cap
-
Website
http://www.cyclacel.com
Introduction

Cyclacel Pharmaceuticals, Inc. is a clinical stage biopharmaceutical company, which engages in the provision of cell cycle, transcriptional regulation and DNA damage response biology to develop medicines for cancer and other proliferative diseases. It operates through the United States and United Kingdom geographical segments. The company builds a biopharmaceutical business, which is focused on hematology and oncology based on a pipeline of novel drug candidates. Its products include CYC065, seliciclib, and sapacitabine. The company was founded by Ronald J. Berenson, David Philip Lane, and David Glover on August 13, 1996 and is headquartered in Berkeley Heights, NJ.

A Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-10-21
Last Posted Date
2021-12-22
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
103
Registration Number
NCT00999401
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

A Study of Oral Sapacitabine in Patients With Previously Treated Non-Small Cell Lung Cancer

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2009-04-22
Last Posted Date
2021-12-22
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
62
Registration Number
NCT00885963
Locations
🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

🇺🇸

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients

First Posted Date
2008-01-10
Last Posted Date
2024-06-04
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
105
Registration Number
NCT00590187
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

🇺🇸

Vanderbilt U Medical Center, Nashville, Tennessee, United States

and more 12 locations

A Phase I Pharmacologic Study of CYC116, an Oral Aurora Kinase Inhibitor, in Patients With Advanced Solid Tumors

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2007-11-20
Last Posted Date
2021-12-22
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
25
Registration Number
NCT00560716
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

🇺🇸

South Texas Accelerated Research Therapeutics, San Antonio, Texas, United States

A Randomized Phase II Study of Oral Sapacitabine in Patients With Advanced Cutaneous T-cell Lymphoma

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2007-05-22
Last Posted Date
2021-12-22
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
16
Registration Number
NCT00476554
Locations
🇺🇸

Stanford University Hospitals and Clinics, Stanford, California, United States

🇺🇸

Timothy Kuzel, M.D., Chicago, Illinois, United States

🇺🇸

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Safety and Pharmacology Study of Sapacitabine to Treat Advanced Leukemias or Myelodysplastic Syndromes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2006-09-26
Last Posted Date
2021-12-13
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
47
Registration Number
NCT00380653
Locations
🇺🇸

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Efficacy Study of Oral Seliciclib to Treat Non-Small Cell Lung Cancer

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2006-09-06
Last Posted Date
2021-12-22
Lead Sponsor
Cyclacel Pharmaceuticals, Inc.
Target Recruit Count
187
Registration Number
NCT00372073
Locations
🇺🇸

Pasco Hernando Oncology, New Port Richey, Florida, United States

🇺🇸

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

🇺🇸

Pacific Coast Hematology Oncology Group, Fountain Valley, California, United States

and more 17 locations
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