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NATIONAL INSTITUTE ON DRUG ABUSE AND ADDICTION

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Semaglutide Therapy for Alcohol Reduction (STAR)

Phase 2
Recruiting
Conditions
Addiction
Alcohol Use Disorder
Interventions
Behavioral: Take Control
First Posted Date
2023-08-29
Last Posted Date
2025-05-14
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
52
Registration Number
NCT06015893
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Spironolactone in Alcohol Use Disorder (SAUD)

Phase 1
Recruiting
Conditions
Alcohol Use Disorder
Interventions
Other: Placebo
First Posted Date
2023-04-11
Last Posted Date
2025-05-20
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
20
Registration Number
NCT05807139
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Development and Validation of Learning and Decision-Making Tasks

Recruiting
Conditions
Normal Physiology
Interventions
Device: MRI
First Posted Date
2023-02-01
Last Posted Date
2025-05-14
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
550
Registration Number
NCT05707806
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol

Recruiting
Conditions
Healthy Volunteers
Vaping Teens
First Posted Date
2023-01-03
Last Posted Date
2025-04-20
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
1600
Registration Number
NCT05669716
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Orexin s Role in the Neurobiology of Substance Use Disorder

Not Applicable
Recruiting
Conditions
Nicotine Dependence
Interventions
First Posted Date
2022-11-30
Last Posted Date
2025-03-27
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
140
Registration Number
NCT05630781
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Defining Neurobiological Links Between Substance Use and Mental Illness

Not Applicable
Recruiting
Conditions
Substance Use Disorder
Major Depressive Disorder
Normal Physiology
Interventions
Other: Placebo Nicotine Patch
First Posted Date
2022-09-14
Last Posted Date
2025-05-20
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
420
Registration Number
NCT05538910
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Real-world Momentary Assessment of Kratom Use Accompanied by Product Assays: A Natural-history Study for Interdisciplinary Characterization of Kratom Use and Pharmacology

Completed
Conditions
Fatigue
Substance Use Disorders
Chronic Pain
First Posted Date
2022-07-14
Last Posted Date
2023-06-12
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
395
Registration Number
NCT05457803
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Evaluation of the Interactions of Cannabidiol (CBD) With Morphine

Phase 1
Recruiting
Conditions
Opioid Use Disorder
Interventions
First Posted Date
2021-12-03
Last Posted Date
2024-03-27
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
60
Registration Number
NCT05143424
Locations
πŸ‡ΊπŸ‡Έ

AltaSciences, Overland Park, Kansas, United States

Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD

Phase 2
Completed
Conditions
Opioid-Use Disorder
Interventions
Other: Placebo
First Posted Date
2020-03-20
Last Posted Date
2025-04-10
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
5
Registration Number
NCT04316559
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder

Phase 1
Completed
Conditions
Alcohol Use Disorder
Interventions
Other: Placebo
First Posted Date
2019-04-01
Last Posted Date
2025-01-15
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
21
Registration Number
NCT03896516
Locations
πŸ‡ΊπŸ‡Έ

National Institute on Drug Abuse, Baltimore, Maryland, United States

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