RAPT Therapeutics Initiates Phase 2a Trial of RPT193 for Moderate-to-Severe Asthma
RAPT Therapeutics has commenced a Phase 2a clinical trial to assess RPT193, an oral, once-daily monotherapy, for treating moderate-to-severe asthma.
JSSSTU's JNANAM Satellite to Study Drug Stability in Space
JSS Science and Technology University (JSSSTU) and IN-SPACe have partnered to launch the JNANAM satellite project for medical applications.
UK Experts Call for Centralized Genomic Database to Accelerate Rare Disease Trial Recruitment
British genetics experts emphasize the critical need for a centralized genomic database to connect rare disease patients with clinical trials, particularly benefiting conditions affecting as few as 20 people nationwide.
Magnetic Pulses Show Promise in Treating Chronic Insomnia
Researchers are developing a handheld device that uses magnetic pulses to treat chronic insomnia by targeting the default mode network (DMN).
Cochlear Cooling Devices Show Promise in Preventing Hearing Loss in Clinical Trials
Researchers at the University of Miami Miller School of Medicine are investigating cooling devices to prevent hearing loss in two NIH-funded clinical trials.
I CAN DO Surgical ACP Trial Updates Ethics Documentation for Implementation Phase
The I CAN DO Surgical ACP trial has updated its ethics and regulatory documentation as it transitions to the implementation phase.
Elahere Demonstrates Significant Survival Benefit in Phase III MIRASOL Trial for Platinum-Resistant Ovarian Cancer
AbbVie's final analysis of the phase III MIRASOL trial confirms Elahere (mirvetuximab soravtansine) provides superior efficacy compared to chemotherapy in folate receptor alpha-positive platinum-resistant ovarian cancer patients.
GSK's Zejula Shows Promising Results in Phase II Mesothelioma Trial with 27% Reduction in Disease Progression
Phase II NERO study demonstrates GSK's Zejula (niraparib) reduced risk of disease progression or death by 27% in relapsed mesothelioma patients compared to standard care.
PhotoPharmics Reaches 50% Enrollment Milestone in Phase 3 Trial Testing Light Therapy for Parkinson's Disease
PhotoPharmics has enrolled 150 participants in its Light for PD Phase 3 clinical trial, evaluating specialized phototherapy for both motor and non-motor symptoms of Parkinson's disease.
Breakthrough Blood Test for Early Ovarian Cancer Detection Enters Clinical Trials in Australia
The University of Queensland is launching a clinical trial of a novel blood test that has shown 94% accuracy in detecting early-stage ovarian cancer, potentially revolutionizing screening for this deadly disease.
AI-Powered 'TrueBlue' Trial Launches to Revolutionize Postnatal Depression Detection
University of Nottingham initiates groundbreaking TrueBlue trial using AI and virtual avatar technology to detect early-stage postnatal depression, offering a modern alternative to traditional clinical scales.
Novel DNA Aptamers Deliver Dual-Action Therapy Against Leukemia Stem Cells
Researchers at University of Illinois have developed drug-carrying DNA aptamers that specifically target leukemia stem cells with a dual mechanism of action, reducing cancer relapse risk.
CU Medicine Introduces Asia's First Histotripsy 2.0 System for Liver Tumour Treatment
The Chinese University of Hong Kong's Faculty of Medicine has received Asia's first Histotripsy 2.0 system, a donation from the Li Ka Shing Foundation, aimed at treating liver tumours. This advanced system, set to serve patients by early 2025, offers more precise focal therapy and supports continuous upgrades. The Foundation, along with CU Medicine and the Prince of Wales Hospital Charitable Foundation, will sponsor 30 patients to undergo this novel treatment, marking a significant step forward in cancer treatment research.
First Patient Receives Novel Stem Cell Therapy in Groundbreaking Sjögren's Disease Trial
University of Wisconsin researchers launch first-of-its-kind Phase 0 clinical trial using patient's own enhanced stem cells to treat salivary gland dysfunction in Sjögren's disease.
Weight Loss Injections Show Promising Anti-Cancer Effects Beyond Weight Reduction
Research presented at the European Congress on Obesity suggests weight loss injections may reduce obesity-related cancer risk by nearly 50%, potentially through anti-inflammatory mechanisms beyond simple weight reduction.
Ulefnersen Shows Unprecedented Recovery in Young Patients with Rare FUS-ALS
Columbia University researchers report that ulefnersen, an experimental drug, demonstrated remarkable efficacy in treating FUS-ALS, a rare genetic form of ALS affecting young people.
Merck Initiates Phase 3 Trial of Bomedemstat for Essential Thrombocythemia
Merck has begun the Phase 3 Shorespan-007 trial to assess bomedemstat, an oral LSD1 inhibitor, in essential thrombocythemia (ET) patients without prior cytoreductive therapy.
AI-Powered Stethoscope Improves Detection of Pregnancy-Linked Heart Failure
A new clinical trial in Nigeria demonstrates that an AI-enhanced digital stethoscope significantly improves the detection of peripartum cardiomyopathy.
Quality of Life Measures Gain Traction in Cancer Clinical Trials
A nationwide clinical trial is assessing the quality of life (QoL) in young Hodgkin lymphoma patients, marking a shift towards accessible and interpretable patient-reported outcomes.
Brain+ Initiates Clinical Trial of BrainBlossom for Mild Cognitive Impairment
Brain+ has commenced a clinical trial to evaluate BrainBlossom, a next-generation cognitive training technology, for individuals with Mild Cognitive Impairment (MCI).