NL-OMON53341尚未招募不适用
MUSCLE study - Mitochondrial dysfUnction: a key player in doxorubicin-induced Skeletal and Cardiac muscLE damage? - MUSCLE
niversitair Medisch Centrum Utrecht0 个研究点目标入组 12 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •Age >= 18 years
- •Patients with large B-cell lymphoma or T-cell lymphoma scheduled for 6
- •full-dose cycles of 1st line immunochemotherapy with cyclophosphamide,
- •doxorubicin, vincristine and prednisone with or without rituximab ((reversed)
- •(R-)CHOP).
- •WHO-performance score 0-2.
- •Patients with sufficient Dutch writing and reading skills.
- •Written informed consent
排除标准
- •Contra-indications for 7T MR scanning
- •Any circumstances that would impede adherence to study requirements or
- •ability to give informed consent.
- •Medical disorders affecting mitochondrial function; e.g., spinal muscular
- •(Other) relevant medical disorders; e.g., comorbidities affecting exercise
- •Being under examination for non-diagnosed disease at the time of
- •investigation.
研究者
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