Comparative effects of high-flow nasal cannula and simple mask during deep sedation with propofol on US-guided radiofrequency ablation of hepatic neoplasm

Intraprocedural PaO2 and the difference of pre- and intraprocedural PaO2 were significantly different between two groups. Intraprocedural PaO2 of mask groups and HFNC were 199.9 (154.3 – 224.9) and 287.0 (191.3 – 379.9) mmHg, respectively (p = 0.009) and the differences of pre- and intraprocedural PaO2 of mask groups and HFNC were, 111.6 (67.4 – 141.8) and 188.5 (100.1 – 280.3) mmHg, respectively (p = 0.009l). The incidence of hypoxic event was not significantly different between two groups. (36% of mask group vs. 25.0% of HFNC group, respectively; p = 0.505). However, the incidence of severe hypoxic event was significantly lower in HFNC group than mask group. (32% of mask group vs. 4.2% of HFNC group, p = 0.045). Intraprocedural PaO2/FiO2 were significantly different between two groups. PaO2/FiO2 of mask group was significantly higher than HFNC group [399.9 (308.6 – 449.7) and 287.0 (191.3 – 379.9) mmHg, respectively (p = 0.005)]. RR was significantly different between two groups (F = 7.944; p = 0.08). There were significant differences in patient’s satisfaction score between two groups. Patients in mask group were more satisfied than HFNC group [60.6 (56.8 – 66) vs. 54.0 (44.0 – 62.0), respectively; p =0.031].