Gaining and sustaining control of Schistosomiasis in Cabo Delgado, Mozambique where the starting prevalence is greater than 25%: a multi-centre randomized intervention trial
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 105,000
研究概览
简要总结
2016 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/27230666 protocol and baseline data 2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/30439945 results 2017 Interim results article in https://doi.org/10.1186/s12879-017-2738-5 Protocol and baseline data for a multi-year cohort study of the effects of different mass drug treatment approaches on functional morbidities from schistosomiasis in four African countries (added 20/01/2023) 2020 Other publications in https://doi.org/10.4269/ajtmh.19-0805 Challenges in Protocol Development and Interpretation of the Schistosomiasis Consortium for Operational Research and Evaluation Intervention Studies (added 20/01/2023) 2020 Other publications in https://doi.org/10.4269/ajtmh.19-0829 Impact of Different Mass Drug Administration Strategies for Gaining and Sustaining Control of Schistosoma mansoni and Schistosoma haematobium Infection in Africa (added 20/01/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Schoolchildren, either male or female, aged 9-12 years, attending the selected schools (in each study year)
- •2. First-year students, either male or female, attending the selected schools (in years 1 and 5)
- •3. Written informed consent signed by parents or legal guardians of the schoolchildren
- •4. Oral assent from schoolchildren
- •5. At least one urine sample provided over three consecutive days from 9- to 12-year-old children each study year
- •6. At least one urine sample provided from first-year students and adults in years 1 and 5
排除标准
- •1. Children not aged 9-12 years (in years 2, 3 and 4)
- •2. Adults in Years 2, 3 and 4
- •3. Children under 9 in Years 2, 3, 4
- •4. No written informed consent by parents or legal guardians of schoolchildren
- •5. No oral assent given by schoolchildren
- •6. No urine sample provided (for 9- to 12-year-old children in each study year; for first-year students and adults in years 1 and 5)