Differences in Physiological Responses of Satiety and Reward After (in)Consistent Calorie Cues.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Food intake
研究概览
简要总结
The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food. Food intake is not only regulated by appetite and satiety signals - external cues also play an important role.
It has been observed that food intake and the pleasure derived from consumption is affected by manipulation of the external cues.
The investigators will assess the contribution of food anticipation (calorie information) and actual consumption of a test food (calorie intake) on in satiety responses (such as ghrelin responses, appetite and subsequent food intake). The investigators expect the information on the amount of calories, rather than the actual amount of calories in the food, to predict the ghrelin responses and the subsequent intake of a second meal.
详细描述
In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •being used to eat breakfast regularly (≥ 5 times a week).
排除标准
- •hypersensitivity for the ingredients of the foods under study;
- •lack of appetite; following an energy-restricted diet or change in body weight > 5 kg; or
- •being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea.
结局指标
主要结局
Food intake
时间窗: 60 min (Ad libitum test meal after 1 hr)
次要结局
- Serum concentrations total ghrelin(60 min (4 samples - every 20 min))