Investigation of the Nature and Prevalence of Mitochondria Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Symptoms of Mitochondrial diseases
研究概览
简要总结
The objective of this research protocol is to continue investigation of the nature and prevalence of mitochondria disease and to aid patients and health care providers in the understanding of these complex disorders.
This research study brings together many clinical sub-specialists to address the etiology of these disorders and to develop more effective approaches for their diagnoses and more reliable prognoses.
详细描述
The non-invasive device named Diffuse Optical Spectroscopy developed at the Beckman Laser Institute is to be used to measure various physiological parameters. Since mitochondria produce most of the energy necessary for cellular function, their efficacy is most important for systems with a high energy demand like the brain, heart, skeletal muscle, kidney, liver, and endocrine tissues. As a result, mitochondria diseases usually manifest as complex, multi-organ disorders, requiring multispecialty investigations.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female all ages group with diagnosis of mitochondrial disorder
排除标准
- •Subjects with visual, auditory and/or neurological problems known to result from toxic or environmental effects
结局指标
主要结局
Symptoms of Mitochondrial diseases
时间窗: Up to 12 weeks
次要结局
未报告次要终点
研究者
Beckman Laser Institute and Medical Center
Virginia Kimonis, MD, MRCP
University of California, Irvine