NCT04407052Unknown2 期
Double Trigger in Patients With Low Proportion of Mature Oocytes. A Randomized Controlled Trial
Riyadh Fertility and Reproductive Health center1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2020年5月30日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Number of oocytes retrieved
研究概览
简要总结
The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the number of mature oocytes in patients with history of low proportion of mature oocytes in previous IVF cycle triggered by HCG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients with history of low proportion of mature oocytes in previous IVF attempt (triggered by HCG).
- •Patients with 6 to 15 mature follicles on the day oocyte trigger in the current IVF-ET attempt
排除标准
- •Endometriosis
研究组 & 干预措施
Double trigger
Experimental
GnRH-agonist and HCG are used to trigger ovulation
干预措施: Double trigger (Drug)
HCG
Active Comparator
HCG is used to trigger ovulation
干预措施: HCG trigger (Drug)
结局指标
主要结局
Number of oocytes retrieved
时间窗: First day after oocyte retrieval
次要结局
- Clinical pregnancy rate(First 5 weeks after oocyte retrieval)
研究者
研究点 (1)
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