Comparison of Pressure and Volume Controlled Ventilation in Terms of Mechanical Power in Upper Abdominal Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- calculation of mechanical power changes in two different ventilation modes
研究概览
简要总结
Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation
详细描述
The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA1-2 , >18 years old patients having upper abdominal surgery
排除标准
- •chronic obstructive lung disease, interstitial lung disease
- •chronic renal failure
- •Child-Pugh > 6 liver disease
- •Patients who don't give consent
- •NYHA > 2 heart failure
结局指标
主要结局
calculation of mechanical power changes in two different ventilation modes
时间窗: change from at the beginning of surgery till the end of surgery
mechanical power will be calculated using the Van der Meijden's formula for pressure support ventilation and Gattinoni's formula for volume controlled ventilation and two mechanical powers will be compared
次要结局
- hospitalisation time(up to 20 days)
- postoperative pulmonary complications(post-operative 7 days)
研究者
Reyhan Nil Kırsan
Principal Investigator
Istanbul University