Comparison of the Effects of Erector Spinae Plane Block and Intrathecal Morphine Administration on Intraoperative Sevoflurane Consumption in Disc Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- Intraoperative Sevoflurane consumption
研究概览
简要总结
In our study, the investigators aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.
详细描述
The amount of volatile anesthetic agents used for anesthesia maintenance can be significantly reduced with potent and long-acting analgesic interventions administered during the preoperative period. Such interventions enable the maintenance of anesthesia with more optimal levels of agents during surgery, providing significant advantages in terms of both patient safety and cost.
Studies have recommended multimodal analgesia approaches involving the Erector Spinae Plane (ESP) block and intrathecal morphine (ITM) injection for various surgical procedures. These two methods, through different mechanisms of action, not only reduce intraoperative anesthetic agent consumption but also play a critical role in postoperative pain management. Although studies have investigated the effects of ESP block and ITM injection on intraoperative volatile anesthetic consumption, there is limited research directly comparing their impacts on volatile anesthetic consumption and postoperative analgesic requirements.
In our study, we aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged over 18 years
- •Patients receiving general anesthesia
- •Patients with an ASA score of I-II
- •Patients undergoing elective surgery for single-level lumbar disc herniation
- •Patients who provided informed consent after being informed
排除标准
- •Patients who did not provide informed consent after being informed
- •Patients over 65 years of age
- •Patients with an ASA score of III or higher
- •Patients with recurrent lumbar disc herniation (LDH)
- •Patients undergoing surgery for multi-level LDH
- •Patients with a body mass index (BMI) of 30 or higher
- •Patients with allergies to morphine or bupivacaine
- •Patients with major cardiac, respiratory, hepatic, renal, neurological, or psychiatric diseases
- •Patients with a history of alcohol or substance abuse
- •Patients with a local infection at the injection site
- •Patients with bleeding diathesis
- •Patients with a history of anticoagulant medication use
- •Patients with contraindications to spinal or regional anesthesia
结局指标
主要结局
Intraoperative Sevoflurane consumption
时间窗: 60 minutes after anesthesia induction
End-expiratory sevoflurane concentration was monitored every 5 minutes for 60 minutes. The mean sevoflurane concentration in the first 60 minutes was calculated.
次要结局
- Rescue analgesic consumption(24 hours postoperatively)
研究者
Yusuf Özgüner
Principal Investigator
Ankara Etlik City Hospital
