A comparative study of lignocaine nebulization with intravenous lignocaine for attenuation of pressor response to laryngoscopy and intubation
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To study and compare the effects of intravenous lignocaine IV 2% (2mg/kg) with nebulization of 2% lignocaine (2 mg/kg) on hemodynamic response to laryngoscopy and endotracheal intubation.
研究概览
简要总结
This is a prospective randomised controlled study to compare the effects of Nebulization Of lignocaine 2% with Intravenous lignocaine 2% in attenuation of response to laryngoscopy and endotracheal intubation. Sample size is 100. Patients posted for elective surgeries under General anaesthesia are randomly divided into two groups, 50 receiving Nebulization of lignocaine and 50 receiving Intravenous lignocaine prior to intubation . Hemodynamic response are recorded in those patients and effects are compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •All ASA 1 and 2 patients between 18-65 years posted for elective surgeries under general anesthesia.
排除标准
- •ASA grade 3 and
- •Diabetic and Hypertensive patients.
- •known history of drug allergy.
- •Pregnant and lactating women.
- •Chronic respiratory and cardiovascular disease.
结局指标
主要结局
To study and compare the effects of intravenous lignocaine IV 2% (2mg/kg) with nebulization of 2% lignocaine (2 mg/kg) on hemodynamic response to laryngoscopy and endotracheal intubation.
时间窗: From shifting on OT table till 15 minutes post endotracheal intubation
次要结局
- To evaluate any side effects with use of this drug in both routes(Baseline)
研究者
Hublikar Hemanth
Mysore Medical College and Research Institute