ISRCTN86185157已完成3 期
A multicentre randomised trial of single dose Radiotherapy compared to Ibandronate for localised metastatic Bone pain
Cancer Research UK (CRUK) (UK)0 个研究点目标入组 580 人开始时间: 2003年6月2日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 580
研究概览
简要总结
2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26242893 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Histologically or cytologically proven underlying primary malignancy of breast, lung or prostate, or sclerotic bone metastases in a patient presenting with a serum Prostate Specific Antigen (PSA) more than 100ng/ml
- •2. Bone metastases confirmed radiologically on plain x-ray, isotope scan, Computed Tomography (CT) or Magnetic Resonance (MR) scan
- •3. Single localised metastatic bone pain receiving optimal analgesics and adjuvant drugs including Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) unless contraindicated.
- •4. Clinical diagnosis of metastatic bone pain for which radiotherapy is indicated
- •5. Aged over 18 yrs with no upper age limit
- •6. Able to comply with pain chart and quality of life assessments
- •7. Able to give written informed consent.
排除标准
- •1. Predicted life expectancy less than three months
- •2. Bisphosphonate treatment within the last six months
- •3. Any previous treatment that contraindicated radiotherapy or ibandronate or that would interfere with the action of either
- •4. Unfit to receive radiotherapy and ibandronate
- •5. Aspirin sensitive asthma in past medical history
- •6. Pregnancy and lactation
研究者
相似试验
已完成
不适用
A pilot study on the effect of niacin on pulmonary arterial pressurePulmonary hypertensionCirculatory SystemPrimary pulmonary hypertensionISRCTN12353191Georgetown University Institutional Review Board49
已完成
3 期
A multicentre randomised trial of radical radiotherapy with carbogen in the radical radiotherapy of locally advanced bladder cancerBladder (advanced)BladderCancerISRCTN45938399Cancer Research UK (CRUK) (UK)
已完成
不适用
A multi-centred randomised trial to assess if adding web-based support to exercise referral schemes for individuals with metabolic, musculo-skeletal and mental health conditions can increase physical activity after 12 monthsISRCTN15644451Plymouth University450
已完成
不适用
The effect of a cognitive behavioural program called ?Michael?s Game? on psychotic symptomsPsychotic disordersMental and Behavioural DisordersISRCTN37178153Geneva University Hospitals (Switzerland)166
已完成
2 期
Predicting Outcome and Measuring Benefit from botulinum therapy in StrokeTopic: Stroke Research NetworkSubtopic: RehabilitationDisease: Drug type, Therapy type, In hospital studyCirculatory SystemStrokeISRCTN03624752niversity College London (UK)28