Analysis of Intersectin Expression in Primary Human Neuroblastomas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- ITSN1 is highly expressed in neuroblastoma tumors and plays an important role in the development/progression of these tumors
研究概览
简要总结
RATIONALE: Studying protein expression in samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat neuroblastoma.
PURPOSE: This laboratory studying is looking at protein expression in tumor tissue samples from patients with neuroblastoma.
详细描述
OBJECTIVES:
- To determine whether intersectin (ITSN1) proteins are present at elevated levels in primary human tumor samples.
OUTLINE: Archived tumor tissue samples are analyzed for intersectin (ITSN1) expression by western blot assays with enhanced chemiluminescence and exposed to X-ray film. The films are scanned, and levels of ITSN1 signal are quantified by densitometry.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
ITSN1 is highly expressed in neuroblastoma tumors and plays an important role in the development/progression of these tumors
次要结局
未报告次要终点