Chronic Effects of Eccentric Training and Heavy-Slow Resistance Training on the Structural, Morphological, Mechanical, and Functional Properties of Muscle and Tendon in Participants With Patellar Tendinopathy
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Tendon Thickness
研究概览
简要总结
This study aims to investigate the effects of two different resistance training interventions on the structural, morphological, mechanical, and functional properties of the thigh muscles (in particular the quadriceps femoris) and the patellar tendon, in participants with current patellar tendinopathy.
详细描述
Patellar tendinopathy is a common musculoskeletal injury among physically active people and athletes, particularly those who play sports that involve high jumps, such as volleyball and basketball. This condition is associated with alterations in the intrinsic properties of the muscle (e.g., cross-sectional area, muscle length) and the patellar tendon (e.g., stiffness, thickness), along with impairments in sports performance (e.g., altered jump height) and tendon pain.
The current gold-standard treatment for tendinopathies is composed mainly of eccentric training, which overall shows a good percentage of remission of the symptoms, but on the other hand, a high percentage of recurrence of said symptoms.
The objectives are to find out if a specific and controlled eccentric training and heavy-slow resistance training, which literature has shown to be a friendly and closer to daily-life movement alternative for management of patellar tendinopathy. Through the assessment of several muscle, tendon, and performance parameters, our study aims to investigate if individually targeted training variables on both training interventions show a better improvement in the intrinsic properties of the anatomical structures, as well as functional and performance parameters like pain level, strength, jump height, etc.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Between 18 and 50 years of age
- •Pain at the inferior pole of the patella, longer than 3 months
- •Active lifestyle (sport/exercise minimum 3 times per week)
- •No previous injuries or surgeries on the affected leg
排除标准
- •Corticoid injections in the last 6 months
- •Current intake of pain or non-steroidal anti-inflammatory drugs
- •Additional tendinopathy treatments in the last 6 months (i.e., physical therapy, shock-wave therapy, drug interventions, etc.)
- •Neuromuscular or cardiovascular associated diseases or conditions
研究组 & 干预措施
Eccentric Training
Participants between 18 and 50 years of age with patellar tendinopathy who will receive the eccentric intervention only.
干预措施: Eccentric Training (Other)
Heavy-Slow Resistance Training
Participants between 18 and 50 years of age with patellar tendinopathy who will receive the heavy-slow resistance training intervention only.
干预措施: Heavy-Slow Resistance Training (Other)
结局指标
主要结局
Tendon Thickness
时间窗: From enrollment to the end of training at 12 weeks
Anteroposterior thickness of the patellar tendon (in milimiters) measures by B-Mode Ultrasound (Aixplorer V12.3 Supersonic Imaging, France) with a SuperLinear 15-4 MHz probe. Three images at the same position will be taken for further analysis with the software ImageJ.
Tendon sitffness
时间窗: From enrollment to the end of training at 12 weeks
Stiffness of the patellar tendon (in kilopascal) will be measured with Shear-Wave Elastrography (Aixplorer V12.3, Supersonic Imaging, France). The measurement site is 0.5cm from the patellar apex, and five videos of 15 seconds will be recorded for further analysis with Matlab.
Tendon CSA
时间窗: From enrollment to the end of training at 12 weeks
Cross-sectional area of the patellar tendon (in centimiters) on its proximal, middle and distal part, will be measured with B-Mode Ultrasound (Aixplorer V12.3, Supersonic Imaging, France). Three images per site, accounting for a total of 9 images, will be taken for further analysis with the software ImageJ.
Fascicle length
时间窗: From enrollment to the end of training at 12 weeks
Length of the fascicles of the vastus lateralis muscle (in centimiters) will be measures with Extended Field of View (Panoramic) B-Mode Ultrasound (Aixplorer V12.3, Supersonic Imaging, France). Five images will be taken for further analysis with the software ImageJ.
Muscle Strength
时间窗: From enrollment to the end of training at 12 weeks
Maximum voluntary isometric torque of the knee extensors (in newton per meters) will be measured with the Isomed2000, Germany device. Three trials will be performed, with three minutes of rest in between, and the trial with the maximum peak torque will be taken for analysis.
1 repetition maximum
时间窗: From enrollment to the end of training at 12 weeks
Maximum strength of the leg press and knee extension exercises (in kilograms) will be measured with the leg press and knee extension devices (compass540, Physiomed, Germany). Participants will perform repetitions with increasing weights, until they can perform a maximum of eight repetitions with a specific weight. This weight will be then used to estimate their maximum 1RM, to further calculate the training loads.
Overall Pain
时间窗: From enrollment to the end of training at 12 weeks
Pain assessed at rest and during a single-leg-decline squat (SLDS) will be assessed with the numerical rating scale of 11 points called Visual Analogue Scale (VAS). Higher values mean higher pain levels.
Functionality
时间窗: From enrollment to the end of training at 12 weeks
Functionality assessed with the VISA-P Questionnaire. This questionnaire includes 10 questions with a score from 0 to 10, for a maximum questionnaire score of 100 points. Higher scores mean better functionality.
次要结局
- Tendon Neovascularization(From enrollment to the end of training at 12 weeks)
- Young's Modulus(From enrollment to the end of training at 12 weeks)
- Muscle Thickness(From enrollment to the end of training at 12 weeks)
- Muscle Stiffness(From enrollment to the end of training at 12 weeks)
- Jump Height(From enrollment to the end of training at 12 weeks)
研究者
Josefina Manieu
Research Assistant - PhD Student
University of Graz