ISRCTN42722501已完成不适用
Impact of standard continous positive airway pressure (CPAP) therapy on arterial hypertension in patients with obstructive sleep apnoea syndrome (OSAS): a prospective randomised interventional clinical trial
Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)0 个研究点目标入组 40 人开始时间: 2009年4月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Apnoea Hypopnoea Index (AHI) greater than or equal to 15/h
- •2. Aged greater than 18 years, either sex
- •3. Patient's signature on informed consent after receiving oral and written information about the study
- •4. Levels of hypertension 1 - 3 and isolated sytolic hypertension
排除标准
- •1. History with hypertentious crisis, known cardiac risks (coronary heart disease [CHD], heart failure, cardiac arrhythmia, congenital heart diseases)
- •2. Level 3 hypertension, unless patient refuses pharmacological treatment
- •3. Medication or drug abuse
- •4. Ongoing hypertension medication
- •5. Intake of any medication affecting sleep (e.g., medication affecting the central nervous system, tranquilisers)
- •6. Alcohol abuse with a daily consumption of greater than 30 g on a regularly basis
- •7. Participation in a pharmalogical clinical trial within 4 weeks prior to enrolment to this study
- •8. Normal blood pressure recordings in ambulatory blood pressure monitoring (ABPM)
- •9. Any psychiatric or neurological sickness which could influence sleep or therapy compliance
- •10. Dysfunction of thyroid gland
- •11. Chronic pain symptoms of any origin
- •12. Acute cardiac, pulmonary or other internal organ diseases
- •13. Chronic cardiac, pulmonary or other internal organ diseases that could influence sleep
- •14. Existing central sleep-related breathing disorder
- •15. Restless legs syndrome (RLS) and/or periodic leg movement sydrome (PLMS); (Periodic Limb Movement Index [PLMI] greater than 10/h)
- •16. Apoplex and/or myocardial infarction history
- •17. Diabetes mellitus
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