跳至主要内容
临床试验/NCT01547039
NCT01547039Unknown不适用

Platelet Reactivity Testing in Association With Perioperative Microembolic Signals During Carotid Endarterectomy

UMC Utrecht1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2012年6月最近更新:
适应症

试验速览

阶段
不适用
发起方
UMC Utrecht
入组人数
200
试验地点
1
主要终点
Microembolic signals (MES)

研究概览

简要总结

The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Al patients undergoing elective carotid endarterectomy

排除标准

  • Patients requiring a blood transfusion prior to surgery
  • Patients with an inappropriate temporal bone window for transcranial Doppler (TCD)
  • Patients on vitamin K antagonists or antiplatelet treatment other then aspirin
  • Patients with an artificial cardiac valve

结局指标

主要结局

Microembolic signals (MES)

时间窗: During and 1 hour following carotid endarterectomy (CEA)

Microembolic signals detected by transcranial duplex (TCD)

次要结局

  • Ischemic stroke(within 30 days postoperative)
  • Asymptomatic perioperative myocardial injury(3 days postoperative)
  • Myocardial infarction(Within 30 days postoperative)

研究者

发起方
UMC Utrecht
申办方类型
Other
责任方
Principal Investigator
主要研究者

Gert Jan de Borst

MD, PhD

UMC Utrecht

研究点 (1)

Loading locations...

相似试验

Platelet Reactivity and MES During CEA | 临床试验