Hypo-hydration, Mood and Cognition: the Effect of the Colour and Type of Drink
试验速览
- 阶段
- 不适用
- 入组人数
- 162
- 试验地点
- 4
- 主要终点
- Mood rating: agreeable / hostile
研究概览
简要总结
Recently changes in mood and cognition have been reported following minor reductions in hydration status. The aim is to explore that such changes in part at least reflect placebo response; therefore the consumption of plain or coloured water will be compared in drinks designed to differ in their ability to rehydrate.
详细描述
162 individuals will be subject to a temperature of 30°C for three hours, and mood and cognition monitored. Randomly on two occasions they will consume no drink or 300ml of plain or red colored water. In addition they will take a capsule containing sodium chloride or a placebo. Mood will be monitored using visual analogue scales and a battery of cognitive tests will be completed on three occasions: attention, episodic and working memory, reactions times. Urine osmolality will be measured at the beginning and end of the study and changes in body mass will be recorded. Changes in functioning will be related to the nature of the drink and changes in osmolality and body mass.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
盲法说明
Salt / placebo will be consumed by capsule under a double-blind procedure
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Do not meet inclusion criteria
研究组 & 干预措施
Sodium chloride / Water
300mg sodium chloride consumed in a capsule on two occasions with 300ml water
干预措施: Salt with / without water (Biological)
Sodium chloride / no water
300 mg sodium chloride consumed
干预措施: Salt with / without water (Biological)
Sodium chloride / colored water
300mg sodium chloride consumed in a capsule on two occasions with 300ml coloured water
干预措施: Salt with / without water (Biological)
Placebo / water
Placebo consumed in a capsule on two occasions with 300ml water
干预措施: Salt with / without water (Biological)
Placebo / no water
Placebo capsule consumed
干预措施: Salt with / without water (Biological)
Placebo / coloured water
Placebo consumed in a capsule on two occasions with 300ml colored water
干预措施: Salt with / without water (Biological)
结局指标
主要结局
Mood rating: agreeable / hostile
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words agreeable/hostile and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
Mood rating: tired / energetic
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words tired / energetic and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
Mood rating: confused / clearheaded
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words confused / clearheaded and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
Mood rating: composed / anxious
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words composed / anxious and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
Mood rating: depressed / elated
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words depressed / elated and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
Mood rating: confident / unsure
时间窗: Changes from baseline after 90 and 180 minutes
A hundred millimetre lines will be anchored with the words confident / unsure and the subject will rate their mood by marking the line.. My measuring in millimetres a score between 0 and 100 will result with a higher score indicating a more positive mood.
次要结局
- Reaction times(Changes from baseline after 90 and 180 minutes)
- Serial Sevens; test of working memory(Changes from baseline after 90 and 180 minutes)
- Episodic memory(Changes from baseline after 90 and 180 minutes)
- Attention: Arrow Flankers(Changes from baseline after 90 and 180 minutes)
研究者
David Benton
Professor
Swansea University