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临床试验/CTRI/2026/03/106475
CTRI/2026/03/106475尚未招募不适用

Behavioral changes and extra-pyramidal symptoms in elderly patients on L-type calcium channel blockers.

BANARAS HINDU UNIVERSITY1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2026年3月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
120
试验地点
1

研究概览

简要总结

The proposed study aims to evaluate the impact of calcium channel blockers and other drugs on elderly patients with a primary focus on identifying the incidence of behavioral changes while secondary objectives include assessing motor disorders determining epidemiologic risk factors and comparing outcomes such as quality of life adverse events and cognitive performance. Elderly patients aged 60 years and above from the Geriatric OPD or ward diagnosed with hypertension or tachycardia and started on calcium channel blockers or other antihypertensives or rate controlling agents including those previously diagnosed but untreated for at least one month will be recruited and followed for one year. Subgroup analyses between those on CCBs alone and those on CCBs combined with others will be performed. Exclusion criteria include dementia HMSE less than 25 established neuropsychiatric disorders serious illnesses such as myocardial infarction or stroke acute conditions requiring hospitalization and significant hearing speech or vision loss. Participants will be categorized into four groups based on drug class and condition. Outcomes will be assessed at baseline 1 month 3 month 6 month and 12 month respectively.

研究设计

研究类型
Observational

入排标准

年龄范围
60.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Elderly patients who are more than/equal to 60 years of age and diagnosed with hypertension or tachycardia/tachyarrhythmia and started on CCBs or other anti hypertensives or started on CCBs or other rate controlling agents and who give consent to participate in the study.

排除标准

  • Patients with below mentioned conditions shall be excluded Associated dementia Established neuropsychiatric disorders at baseline Serious illnesses like myocardial infarction or stroke which may deem recruitment in study unfavorable as per treating geriatrician Serious acute illness requiring hospitalization Significant hearing or speech or vision loss which makes communication impossible.

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Sankha Shubhra Chakrabarti

Institute of Medical Sciences Banaras Hindu University

研究点 (1)

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