NCT05827029进行中（未招募）不适用
Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obese Volunteers: A Randomized Crossover Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- gastric residual volume
研究概览
简要总结
This randomized crossover study compares gastric residual volume after ingestion of carbohydrate drinks and water in obese volunteers. The main question[s] it aims to answer are:
- Is it safe for obese patients to shorten their fasting by allowing preoperative drinks?
- How long is the gastric emptying time in obese patients? Participants also will be evaluated the level of thirst/hungry and blood sugar.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
- •Age 18 - 65 years old
- •BMI ≥ 30 kg/m2
- •NPO for at least 6 hours before the study
排除标准
- •Diabetes Mellitus
- •Chronic kidney disease or End-stage renal disease
- •Use of any medication that affects gastric secretion or emptying (Histamine 2 receptor antagonist eg. Ranitidine/Proton pump inhibitor eg. Omeprazole/Acid neutralization eg. Aluminium hydroxide/Prokinetic eg. Domperidone) within the past 24 hours
- •Gastroesophageal reflux disease
- •Pregnancy
- •History of upper gastrointestinal surgery
- •In diet program or use appetite suppressant drug (eg. Liraglutide, Naltrexone, Phentermine, Diethylpropion) within the past 24 hours
研究组 & 干预措施
Water
Placebo Comparator
干预措施: Preopertive drink (Procedure)
Preoperative carbohydrate drink
Experimental
干预措施: Preopertive drink (Procedure)
结局指标
主要结局
gastric residual volume
时间窗: baseline and every 30 minutes until 2 hours after drinking
changes in gastric residual volume during 2 hours after drinking
次要结局
- POCT glucose(baseline and 120 minutes after drinking)
- thirst and hunger level(baseline and 120 minutes after drinking)
- time to empty gastric antrum(baseline and 120 minutes after drinking)
研究者
Chanatthee Kitsiripant
Asst.Prof.
Prince of Songkla University
研究点 (1)
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