NCT00100113Unknown1 期
Study of Interactions Between GBR 12909 and Cocaine
适应症
相关药物
试验速览
- 阶段
- 1 期
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Heart rate
研究概览
简要总结
The purpose of this study is to assess potential interactions between intravenous (IV) cocaine and 3 doses of GBR 12909.
详细描述
This is Phase 1, double-blind, placebo-controlled human laboratory clinical pharmacology study that will assess the potential interactions between IV cocaine and 3 escalating oral doses of GBR 12909. The primary objective is to determine safety of GBR 12909 administration and if there are significant interactions between GBR 12909 treatment concurrent with IV cocaine infusions.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Must be within 20% ideal body weight and must weigh at least 45 kg.
- •Must understand the study procedures and provide written informed consent.
- •Must meet DSM-4 criteria and are non-treatment seeking at time of study.
排除标准
- •Please contact study site for more information
结局指标
主要结局
Heart rate
次要结局
未报告次要终点
研究者
研究点 (2)
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