Correlation of Perfusion Index with Bispectral Index for depth of anaesthesia in children undergoing elective surgery
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Decrease in anaesthetic requirement with correlation to Perfusion Index
研究概览
简要总结
Perfusion Index is the ratio of pulsatile blood flow signal as percentage of non pulsatile blood flow signal. It is a non invasive, reliable and indirect representation of the peripheral perfusion and circulatory status. During general anaesthesia, peripheral vasodialation is a well known side effect and it induces changes in the amplitude of the pulse plethysmograph waveform which can be recorded using Masimo Radical-7 SET monitor as Perfusion Index and it can be compared with Bispectral Index which has been established as a method of measurement of depth of anaesthesia for induction, maintainence as well as recovery phase. We hypothesized that the Perfusion Index would increase with the induction of general anaesthesia and decrease with emergence in children. Using PI in comparison to BIS may help in developing a useful tool for intraoperative anaesthesia monitoring and the assessment of anaesthetic depth. Although there are limited studies in literature comparing PI and BIS, so we have planned to conduct this study to compare trends of PI in correlation to BIS for depth of anaesthesia and to see changes in PI with time during general anaesthesia. The study is a prospective and observational study with a total of 50 , ASA I or II paediatric patients aged between 2-12 years of either sex scheduled for elective surgery requiring general anaesthesia in supine position.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2.00 Year(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •Paediatric patients belonging to American Society of Anaesthesiologists(ASA) physical status I or II scheduled for elective surgery requiring general anaesthesia in supine position will be enrolled in this study.
排除标准
- •Patients having peripheral circulatory disorder, dyshemoglobinemia(methemoglobinemia, sickle cell anaemia, thalassemia, anaemia), neurological disorders, receiving treatment with antiepileptic medications or stimulants, pre-existing lung or cardiac disease, airway abnormalities, artificial nails, dark pigmentation over fingers or patients having contraindication to the planned anaesthesia technique will be excluded from the study.
结局指标
主要结局
Decrease in anaesthetic requirement with correlation to Perfusion Index
时间窗: baseline, 2 minutes after induction, at airway manipulation, at 5 and 10 minutes following induction of general anaesthesia, at cessation , at eye opening
次要结局
- Correlation of Perfusion Index with Bispectral Index(at baseline, 2 minutes after induction, on airway manipulation, 5 minutes, 10 minutes after induction, cessation of anaesthetic, eye opening)