Non-infectious and Infectious Uveitis Diagnosis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 280
- 试验地点
- 1
- 主要终点
- Analysis of serum angiotensin converting enzyme level
研究概览
简要总结
This study evaluates the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and infectious diseases.
详细描述
Increased serum levels of angiotensin converting enzyme and lysozyme are considered as inflammatory markers for diagnosis of sarcoidosis which is an autoimmune inflammatory disease. Sarcoidosis, ankylosing spondylitis and Behcet's disease are the most common autoimmune inflammatory diseases involving the eye.
Elevated serum angiotensin converting enzyme levels have also been reported in tuberculosis. Syphilis and tuberculosis are the most common infectious diseases involving the eye.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 9 Years 至 86 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects have ocular inflammation diagnosed as sarcoidosis, ankylosing spondylitis, behcet's disease
- •Subjects have ocular infection diagnosed as tuberculosis and syphilis
- •Subjects have refractive errors only
排除标准
- •Subjects using ACE inhibitors, systemic steroids, immunosuppressive or immunomodulatory therapies
研究组 & 干预措施
serum angiotensin converting enzyme
spectrophotometric assay
干预措施: spectrophotometric assay (Other)
serum angiotensin converting enzyme
spectrophotometric assay
干预措施: radial immunodiffusion (Other)
serum lysozyme
radial immunodiffusion
干预措施: spectrophotometric assay (Other)
serum lysozyme
radial immunodiffusion
干预措施: radial immunodiffusion (Other)
结局指标
主要结局
Analysis of serum angiotensin converting enzyme level
时间窗: 1 day
次要结局
- Analysis of serum lysozyme level(1 day)
研究者
Ozlem Sahin
Medical Doctor, Specialist in Ophthalmology, Uveitis and Ocular Immunology
Dünyagöz Hospital