Impact of Radiofrequency Ablation Therapy in Coronary Artery Bypass Grafts Surgery on Outcomes in Patients With Myocardial Infarction Related Ventricular Arrhythmia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 180
- 试验地点
- 3
- 主要终点
- Morbidity of potential malignant ventricular arrhythmia
研究概览
简要总结
Patients with myocardial infarction related potential malignant ventricular arrhythmia have high risk of sudden death. The aim of this clinical trial is evaluating therapeutic efficacy of unipolar or bipolar radiofrequency ablation in Coronary Artery Bypass Grafts (CABG) Surgery, which can reduce myocardial ischemia and block reentry circuits of ventricular arrhythmia at the same time. The observation indexes include the morbidity of potential malignant ventricular arrhythmia and major adverse cardiovascular events in mid-long-term after CABG surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patients have been receiving coronary artery bypass grafts from 2015.1-2017.12
- •The patients had old myocardial infarction related potential malignant ventricular arrhythmia
- •Anti-arrhythmic drug treatment is invalid
- •All enrolled patients must being signed the informed consent
排除标准
- •Severe heart failure( ejection fraction under 35%)
- •Patients with acute myocardial infarction
- •Patients with ICD implanted
结局指标
主要结局
Morbidity of potential malignant ventricular arrhythmia
时间窗: 1 year after surgery
The morbidity of potential malignant ventricular arrhythmia in 1 year after surgery
次要结局
- Morbidity of major adverse cardiovascular events(1 year after surgery)
研究者
Yang Yu
Deputy Director of Cardiac Surgery, Principal Investigator,Clinical Professor
Beijing Anzhen Hospital