Does Video Game Play Induce Plasticity in the Visual System of Adults With Amblyopia?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Amblyopic vision
研究概览
简要总结
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This study uses psychophysical measures to study neural plasticity in adults with amblyopia.
详细描述
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. Our previous findings (see CITATIONS) show that the adult amblyopic brain is still plastic and malleable, suggesting that active approach is potential useful in treating amblyopia. The goal of this project is to assess the limits and mechanisms of neural plasticity in amblyopic spatial vision. This study uses psychophysical measures to study neural plasticity in adults with amblyopia. Research participants will be asked to play video games with the amblyopic eye for a period of time. A range of visual functions will be monitored during the course of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults with amblyopia (Age >15 years)
- •Amblyopia: interocular visual acuity difference of at least 0.1 logMAR
- •All forms of amblyopia: Strabismic, anisometropic, refractive, deprivative, meridional amblyopia
排除标准
- •Any ocular pathological conditions (eg macula abnormalities, glaucoma), nystagmus
结局指标
主要结局
Amblyopic vision
时间窗: 9 months
Improvement in amblyopic vision : visual acuity and stereoacuity
次要结局
- Temporal vision(9 months)
- Spatial vision(9 months)
研究者
Roger Winghong Li
Research Specialist
University of California, Berkeley