The effect of sitagliptin on brown adipose tissue and whole-body metabolism in overweight pre-diabetic men - SitaBAT study

eiden University Medical Center0 个研究点开始时间: 2014年10月15日最近更新: 2016年11月14日

试验速览

暂无简介。

•- Male volunteers, 30 Caucasians, born in the Netherlands
•- Age: 35-50 years
•- BMI = 25 and = 30 kg/m2
•- Plasma glucose levels 2 h after OGTT between 7.8 and 11 mM (e.g. impaired glucose tolerance)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 30
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•- Diabetes mellitus (determined on basis of oral glucose tolerance test (OGTT) defined by ADA criteria (22)
•- BMI > 30 kg/m2 or < 25 kg/m2
•- Plasma glucose levels 2 h after OGTT < 7.8 mM or > 11,1
•- Use of medication known to influence glucose and/or lipid metabolism or BAT activity (e.g. beta blockers)
•- Any significant chronic disease
•- Renal, hepatic or endocrine disease
•- Participation in an intensive weight-loss program or vigorous exercise program during the last year before the start of the study
•- Difficulties to insert an intravenous catheter
•- Recent participation in other research projects (within the last 3 months), participation in 2 or more projects in one year

发起方

eiden University Medical Center