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临床试验/NCT04985591
NCT04985591已完成早期 1 期

The Effect of Liposuction on Menses: a Retrospective Study

Shanghai Jiao Tong University School of Medicine0 个研究点目标入组 516 人开始时间: 2016年6月14日最近更新:
适应症

试验速览

阶段
早期 1 期
状态
已完成
发起方
入组人数
516
主要终点
menstrual irregularity

研究概览

简要总结

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • patients who were in 18-55 and have a regular menses -

排除标准

  • Patients who were younger than 18 years old or older than 55 years old, who were in the perimenopausal or postmenopausal stage or who had menstrual irregularity before plastic surgery were excluded from both groups.

结局指标

主要结局

menstrual irregularity

时间窗: three months

to detect any change in the menses during the following 3 months, post surgery

次要结局

未报告次要终点

研究者

发起方
Shanghai Jiao Tong University School of Medicine
申办方类型
Other
责任方
Principal Investigator
主要研究者

Qing-FengLi Li,MD

Professor

Shanghai Jiao Tong University School of Medicine

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