NL-OMON39235已完成不适用
Genetic regulation of stress responsivity as a risk factor for schizophrenia and bipolar disorder. ;Subtitle: The association of (epi)genetic factors on the hormonal and autonomic stress response after psychosocial stress - Epistress study
niversitair Medisch Centrum Utrecht0 个研究点目标入组 220 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 220
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •1. Schizophrenia patients (n=50)
- •2. Bipolar I disorder patients (n=50)
- •3. Healthy co-twin of monozygous twins discordant for bipolar disorder (n=20)
- •4. Healthy volunteers groupwise matched for age, gender, smoking, alcohol use, caffeine intake and drug use (n=50)
- •5. Healthy siblings of bipolar I disorder patients (n=50)
排除标准
- •General exclusion criteria are:
- •- speech impairments
- •- lack of fluency in the Dutch language
- •- Less than 3 Dutch grand parents;Acute exclusion criteria are:
- •- any acute illness
- •- having a severe cold
- •- recent physical exertion within the last 2 hours
- •- large meal within the last 2 hours
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