NCT01067664已完成不适用
The Effect of Serum Progesterone Levels on the Day of hCG Administration on the Probability of Pregnancy in Patients Treated by IVF Using GnRH Antagonists and Recombinant Gonadotrophins
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- Clinical pregnancy, defined as ultrasound evidence of fetal heart activity at 6-8 weeks of gestation
研究概览
简要总结
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF with the use of GnRH antagonists and recombinant gonadotrophins.
There has been evidence, that increased serum levels of progesterone are associated with a decreased probability of pregnancy after IVF.
This study will attempt to explore the role of progesterone on the outcome of IVF, by closely monitoring its levels during the late follicular phase.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age < 40 years
- •Basal FSH < 12 IU/L
- •Basal P < 1.6 ng/mL
排除标准
- •Presence of cystic formations at the ovaries during the basal ultrasound scan (prior the initiation of stimulation)
- •Women with polycystic ovaries syndrome (PCOS)
- •Women with Stage III-IV Endometriosis
- •Women with a pathological condition of the adrenal glands
结局指标
主要结局
Clinical pregnancy, defined as ultrasound evidence of fetal heart activity at 6-8 weeks of gestation
时间窗: At 6-8 weeks of gestation
次要结局
- Pregnancy (defined as a b-hCG> 25 IU/L)(12 days after embryo transfer)
研究者
研究点 (1)
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