ITMCTR2100004780招募中1 期
Study on the brain central mechanism of analgesic effect of opposing needling on total knee arthroplasty based on resting BOLD-fMRI
Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 50 至 75（—）
- 性别
- All
入选标准
- •(1) 50 to 75 years of age.
- •(2) Osteoarthritis of knee joint was diagnosed and unilateral total knee arthroplasty was performed under general anesthesia in hospital. no surgical contraindications, and agreed to participate in this trial.
- •(3) the American Association of Anesthesiologists (ASA) is classified as I or II.
- •(4) all the affected limbs were right knee.
- •(5) all of them are right-handed.
- •(6) consent and sign the informed consent form.
排除标准
- •(1) There was deep venous thrombosis or swelling of lower extremities before operation.
- •(2) Severe arrhythmias, heart failure, chronic obstructive pulmonary disease, epilepsy, mental illness.
- •(3) Patients with brain injury were found after baseline fMRI examination.
- •(4) There were obvious mood swings within 24 hours before fMRI scan.
- •(5) Drinking alcohol, coffee, strong tea, etc., within 24 hours before fMRI scan.
- •(6) During fMRI scan, severe structural or deterministic injuries were found on both sides of the skull.
- •(7) If acute or serious events or adverse events occur during the study, they should not continue to participate in the trial.
- •(8) Patients who received other related treatments on their own during the trial.
- •(9) Poor compliance, repeated explanations are still unwilling to participate in the test, or unable to complete the test cycle.
研究者
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