Effect of Different Liquids Intake in Vasovagal Reaction After Whole Blood Donation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 6,250
- 试验地点
- 1
- 主要终点
- vasovagal reaction rate
研究概览
简要总结
we compared the effect of 3 different kinds of liquids (water, Oral Rehydration Salt 3 and white granulated sugar water) intake in Vasovagal Reaction After Whole Blood Donation
详细描述
Vasovagal reaction is the most common type of blood donation reaction. The main cause of this reaction is the decrease of blood volume. Therefore, fluid supplement before blood donation has been proved to be effective in preventing the vagal reaction after blood donation. It was proved that isotonic (sugar & salt) drink intake before blood donation had a significant effect on reducing vasovagal reaction.
However, in 2002, WHO recommended the new reduced osmolarity rehydration formula with better taste. Oral Rehydration Salt 3 has been produced according to WHO formula with standard ingredient and easy to prepare. In addition, in Guangdong culture, sugar water is regarded as a tonic, more easily accepted. So, the aim of our study was to compare the effects of 500 ml water with Oral Rehydration Salt 3, white granulated sugar and conventional recommended water intake prior to blood donation on blood donation reaction after whole blood donation, in order to understand the effect of different liquid supplement on blood donation reaction and the willingness of blood donation again.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All blood donors donated whole blood in Guangzhou Blood Center during study.
排除标准
- •Blood donors who were deferral by blood screening result and other situations.
研究组 & 干预措施
Oral Rehydration Salts Power (iii)
Dissolve 2 packs of Oral Rehydration Salts Power (iii) (5.125g/pack) in 500ml water and let the subjects drink it up in 20 minutes prior to donation.
干预措施: Oral Rehydration Salts power (iii) (Drug)
water with white granulated sugar
Dissolve 2 packs of Taikoo white granulated sugar (5g/pack) in 500ml water and let the subjects drink it up in 20 minutes prior to donation.
干预措施: water with white granulated sugar (Dietary Supplement)
recommended water intake
Recommend the subjects to drink up 500ml water in 20 minutes prior to donation.
干预措施: water (Dietary Supplement)
结局指标
主要结局
vasovagal reaction rate
时间窗: 1-3days
vasovagal reaction rate in three groups
次要结局
- rate of willingness to donate blood again(3days)