NCT01239277已完成不适用
Combined Nutrient Intake and Muscle Protein Synthesis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Muscle protein synthesis
研究概览
简要总结
Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether combined nutrient intake plays an important role in stimulation of the muscle protein growth in elderly people; and whether it represent effective strategies to overcome the impaired muscle protein synthesis in elderly when compared with young subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 70 Years 至 85 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •70-85 years or 18-30 years
- •BMI < 30
排除标准
- •Type II diabetes
- •All co morbidities interacting with mobility and muscle metabolism of the lower limbs
- •Use of anticoagulants
- •Patients suffering from Phenylketonuria
- •Participation in any regular exercise programme
结局指标
主要结局
Muscle protein synthesis
时间窗: 6 h postprandial period
Muscle protein synthesis will be expressed as fractional synthetic rate (FSR) by dividing the increment in enrichment in the product, i.e. protein-bound C13phe, by the enrichment of the precursor (=plasma availability).
次要结局
未报告次要终点
研究者
研究点 (1)
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