NCT05609565已完成4 期
Hybrid Anesthesia for Ambulatory Knee Arthroscopy Using Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone: a Randomized Controlled Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The duration of motor block (minutes)
研究概览
简要总结
- Although bupivacaine is safe and has a low rate of transient neurologic symptoms, the prolonged sensory and motor block is a drawback for day-case spinal anesthesia.Intrathecal hyperbaric prilocaine causes a much shorter motor block, with a similar onset time and lower inter-individual variability in motor block duration. Furthermore, the peripheral nerve block is used as an adjunct to the spinal anesthesia to prolong the surgical anesthetic conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) score I-II.
- •Body mass index < 35 kg/m2
排除标准
- •Patient's refusal.
- •Known coagulopathy.
- •Known peripheral neuropathy or neurological deficits.
- •Known allergy to study drugs.
研究组 & 干预措施
Group 1
Active Comparator
干预措施: spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine (Drug)
Group 2
Active Comparator
干预措施: spinal anesthesia with bupivacaine (Drug)
结局指标
主要结局
The duration of motor block (minutes)
时间窗: 24 hours postoperatively
The duration of motor block (minutes)
次要结局
未报告次要终点
研究者
Ibrahim Mamdouh Esmat
Assistant Professor of Anesthesia and Intensive Care Department, Faculty of Medicine, Ain- shams University, Cairo, Egypt.
Ain Shams University
研究点 (1)
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