PACTR202009811610400尚未招募未知
Continuous vs. intermittent beta-lactam dosing in critically ill patients with sepsis: A randomized controlled trial.
Applied for and awaiting approval0 个研究点目标入组 408 人开始时间: 2019年11月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 408
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 1 Month(s) 至 23 Month(s)（—）
- 性别
- All
入选标准
- •All patients, adult and paediatric, admitted to the intensive care unit with sepsis
- •Prescription of one of four beta lactam antibiotics by treating doctor:
- •1.Amoxicillin- clavulanate
- •2.Piperacillin-tazobactam
- •3.Meropenem
- •4.Imipenem
- •Anticipated ICU at least 48 hours.
排除标准
- •Less than 1 month old
- •Chronic renal failure (eGFR<30ml/min)
- •Patient admitted and already on renal replacement therapy
- •Inadequate intravenous access
- •Infections in which standard recommended antibiotic duration is > 14 days (eg: infective endocarditis, osteomyelitis)
- •Patients receiving palliative care at study assessment
- •Patient previously enrolled on this study
- •Declined consent
研究者
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