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临床试验/NCT00472121
NCT00472121已完成不适用

The Precision and Arm-to-Arm Variation og Mechanomyography and Acceleromyography for Monitoring the Neuromuscular Block During Anesthesia, A Randomized Controlled Study

Rigshospitalet, Denmark1 个研究点 分布在 1 个国家开始时间: 2007年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
试验地点
1
主要终点
Precision at the contralateral arms using the average residual coefficient of variation over subsequent linear regressions (detrending) over time

研究概览

简要总结

The purpose of the study is the examine the precision of acceleromyography and mechanomyography during recovery from a neuromuscular blocking agent and to examine whether there is any difference in monitoring block at the dominant or non-dominant arm. Our hypothesis is that there is no significant difference in neither the precision nor the level of block in the contralateral arms.

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA I-III
  • General anesthesia >1 hour
  • Surgery in supine position w. possibility of monitoring the neuromuscular block at both arms (n. ulnaris stimulation/thumb response)
  • Written informed content

排除标准

  • Neuromuscular disorders, hepatic and renal dysfunction
  • Medication expected to interfere with the neuromuscular blocking agent
  • Allergy to any medication used during anaesthesia
  • Body weight less or exceeding 20% of ideal body weight
  • Pregnancy or breastfeeding

结局指标

主要结局

Precision at the contralateral arms using the average residual coefficient of variation over subsequent linear regressions (detrending) over time

次要结局

  • Bias and limits of agreement between control TOF, reappearance of T1, T2, T3, T4
  • Time to TOF 0.9 and 1.0 with and without normalization
  • Time to stable T1 and stable TOF
  • T1 height at reappearance of T1-T4
  • Interval 25-75%
  • Time to T1=25%

研究者

申办方类型
Other

研究点 (1)

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