ACTRN12620001131943已完成4 期
Investigating the post-operative opioid use of patients who received intraoperative methadone compared with those who received conventional potent opioids during laparoscopic gynaecological surgery - a double blind randomised controlled trial.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 69
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 78 Years（—）
- 性别
- All
入选标准
- •Adults undergoing general surgery laparoscopy as well as gynaecology laparoscopy at Albury and Wodonga Hospitals
- •-Planned same-day discharge
- •-Able to speak and read English
排除标准
- •-Morbid obesity
- •-Obstructive sleep apnoea, treated with CPAP, or diagnosed but untreated
- •-Significant renal or liver dysfunction
- •-Pregnant or breastfeeding women
- •-Preoperative opioid dependence
- •-Known or suspected allergy to methadone
- •-Anaesthetist wish to avoid methadone administration for any reason
- •-Undergoing laparoscopic bowel resection or laparoscopic nephrectomy
- •-Undergoing emergency laparoscopic operations (e.g. appendicectomy, ectopic pregnancy)
- •-Patients with long QT syndrome, and any on whom a preop ECG reveals a long QT interval
- •-Anyone already on an SSRI (serotonin syndrome risk)
研究者
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