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临床试验/NCT00447200
NCT00447200已完成不适用

Study of the Natural Variation in Strokevolume, and Investigation in the Number of Cycles Necessary to Find a 10% Strokevolume Variation Using Esophageal Doppler

Rigshospitalet, Denmark1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2007年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Strokevolume variation before fluid optimization

研究概览

简要总结

We would like to investigate the natural variation in the strokevolume of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in strokevolume, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

详细描述

We would like to investigate the natural variation in the strokevolume(SV) of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in SV, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

Also we will compare the variation in SV both before and after the patients have been fluid optimized, using an algorithm of 10% increase in SV in order to receive another fluid bolus. The equipment used, will be the CardioQ from Deltex medical.

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Planned abdominal surgery

排除标准

  • Oesophageal pathology,
  • Age >90 yr or <18 yr,
  • Alcohol abuse,
  • Aneurism in thoracic aorta

结局指标

主要结局

Strokevolume variation before fluid optimization

Strokevolume variation after fluid optimization

Number of cycles needed in order to detect a 10% strokevolume increase after fluid bolus of 200ml Voluven.

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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