Pleth Variability Index as Predictors of Fluid Responsiveness in Modified Prone Position(Concord Position) or Knee-chest Position
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- To assess influence of the position change on PVI and other variables(PPV, SVV)
研究概览
简要总结
To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation. Furthermore, modified prone position could influence on dynamic variables including stroke volume variation(SVV), pulse pressure variation(PPV) and PVI.
详细描述
Objective
To compare measurements of pleth variability index (PVI), pulse pressure variation (PPV) and stroke volume variation (SVV) to predict fluid responsiveness in modified prone position or knee-chest position (concord position) for cervical operation.
To identify Influence of the modified prone position (concord position) on these variables.
Method
- To assess influence of the position change on PVI and other variables(PPV, SVV)
- To assess PVI to predict fluid responsiveness at modified prone position
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anaesthesiologists'(ASA) physical status 1-3
- •patients who received cervical operation in modified prone position or knee-chest position
排除标准
- •Valvular heart disease
- •Congestive heart failure, reduced left ventricular function ( Ejection fraction < 40%)
- •Moderate grade of pulmonary disease
- •Arrhythmia (atrial fibrillation, atrial flutter.. etc.)
- •body mass index > 30 or < 15 kg/m2
结局指标
主要结局
To assess influence of the position change on PVI and other variables(PPV, SVV)
时间窗: 1.supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 min after crystalloid 4 ml/kg loading / 3. modified prone position (baseline)
When position change from supine to modified prone position, to assess the change of PVI and other variables. The correlation of PVI and cardiac output during this change.
次要结局
- To measure dynamic variables (pulse pressure variation, stroke volume variation and pleth variability index) in modified prone position(1. Supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 minute after a position change to prone 3. before and after fluid loading)
研究者
Heesun Park
Clinical instructor of Anesthesiology and Pain department
Asan Medical Center