Comparative Study Between Oral Ivabradine Versus Oral Propranolol for Induced Hypotension in Functional Endoscopic Sinus Surgery
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- change in blood loss
研究概览
简要总结
the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 18 - 60 years.
- •Patients of both genders.
- •ASA grade I - II .
排除标准
- •Patient refusal.
- •Any contraindication to medication included in the study .
- •Patients with allergy to medication included in the study.
研究组 & 干预措施
Ivabradine group
干预措施: oral Ivabradine (Drug)
propranolol group
干预措施: oral Propranolol (Drug)
结局指标
主要结局
change in blood loss
时间窗: immediately after the surgery
Estimated blood loss in millilitres per hour is calculated by subtracting the volume of total irrigation used during the case from the total amount of fluid in the suction canister at the end of surgery in addition, pre-weighing and post-weighing of sponges and oropharyngeal packs were also done and dividing by surgical time in hours. assessment of blood loss by Boezaart and van der Merwe Grading System for bleeding during Endoscopic Sinus Surgery
次要结局
未报告次要终点
研究者
Ahmed talaat ahmed aly
clinical professor
Assiut University