The Muscle Protein Synthetic Response Following the Ingestion of a Single Bolus of Algal Protein When Compared to Fungal Protein in Healthy Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Muscle Protein Synthesis
研究概览
简要总结
Dietary protein intake is vital for the maintenance of skeletal muscle mass and health. The production of animal-based proteins sources is associated with growing environmental and ethical challenges. As such, sustainable alternatives are needed. Algae are sustainably produced high-protein sources and it is predicted that algae will become one of the most consumed proteins in the next decades. However, the effects of algae on the stimulation of muscle mass growth are unknown. Therefore, we aim to assess the rate of digestion and absorption, and the effects on muscle growth of two types of algae (spirulina and chlorella) when compared to a sustainable non-animal derived fungal reference protein (mycoprotein), a source known to elicit a robust anabolic response.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 18.5 and 30
- •Recreationally active (<3 times per week structured resistance exercise training)
排除标准
- •Any metabolic impairment
- •Any cardiovascular impairment
- •High blood pressure (>140/90 mmHg)
- •A personal history of epilepsy, seizures or schizophrenia
- •Chronic (>1 month) use of over the counter pharmaceuticals
- •Chronic (>2 months) use of amino acid or protein supplements
- •Allergic to Quorn/mycoprotein or algae products
结局指标
主要结局
Muscle Protein Synthesis
时间窗: 7.5 hours
The rate of synthesis of new muscle protein (Fractional Synthetic Rate %/h)
次要结局
- Plasma Amino Acid Kinetics(7.5 hours)
- Blood Glucose(7.5 hours)
- Serum Insulin(7.5 hours)
- mTOR phosphorylation(7.5 hours)