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临床试验/NCT06431334
NCT06431334招募中不适用

Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique

McGill University2 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2024年6月21日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
8
试验地点
2
主要终点
13CO2 Excretion

研究概览

简要总结

Masters level cyclists are a population above the age of 35 years who frequently participate in prolonged as well as heavy-volume training. Like most endurance-trained athletes, a greater recommended dietary allowance (RDA) for protein of 1.2-1.4 g/kg/bw is suggested.

Dietary protein intake is vital for maximizing the benefits of training and ensuring optimal recovery. Dietary recommendations traditionally have been determined through nitrogen balance techniques, however, recent research indicates how this method is potentially underestimating protein requirements. Therefore, there is a need to reassess current dietary recommendations in order to meet the demands of physical activity for highly active populations.

Recent efforts to understand protein requirements during rest and following exercise have been completed using the indicator amino acid technique (IAAO). This non-invasive method is reported to provide a robust measure of protein requirements. However, there is limited work in older (≥60 years) active populations.

The purpose of this study is to measure the protein requirements in master cyclists, following an endurance training session, using the non-invasive IAAO technique.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
Male
接受健康志愿者

入选标准

  • 18.5< BMI <35 kg/m^2
  • Overtly healthy masters level cyclists ≥65 years
  • Masters level cyclist training (>4 days per week; ~100 km per week)
  • Body mass stable over previous 6-months
  • Availability for multiple metabolic trials (~7 trials)
  • Ability to travel to and from laboratory facility

排除标准

  • Recent history of weight loss or weight gain (>5% body weight)
  • Uncontrolled hypertension
  • ≥2 chronic diseases (e.g. diabetes, osteoporosis, dyslipidemia)
  • Acute illness that could affect protein metabolism (HIV, renal dysfunction, influenza)
  • Currently using anti-inflammatory medications
  • Inability to adhere to study protocol (i.e., alcohol, caffeine, dietary restrictions)
  • Regular tobacco user
  • Illicit drug use
  • Habitually ingesting ≥3 g/kg/bw

研究组 & 干预措施

Masters Level Cyclists

Experimental

Participants are to be randomly assigned varying levels of amino acid intakes ranging between 0.2 to 2.8 g/kg/d

干预措施: Amino Acid Intake (Dietary Supplement)

结局指标

主要结局

13CO2 Excretion

时间窗: 7-weeks

Measured by continuous-flow isotope ratio mass spectrometry

次要结局

  • L[13C]phenylalanine Oxidation(7-weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tyler Churchward-Venne

Associate Professor

McGill University

研究点 (2)

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